I-Lorcaserin HCL powder (1431697-94-7) hplc =99% | Ukulahlekelwa Ukulahlekelwa Kwemvelo
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I-Lorcaserin HCL powder

Isilinganiselwa: SKU: 1431697-94-7. Isigaba:

I-AASraw ingumkhiqizi ochwepheshe we-Lorcaserin hydrochloride powder eluhlaza enelebhu ezimele kanye nefektri enkulu njengokusekela, konke ukukhiqizwa kuzokwenziwa ngaphansi komthetho we-CGMP kanye nesistimu yokulawula ikhwalithi elandelekayo. Uhlelo lokuhlinzeka luzinzile, kokubili ama-oda okuthengisa kanye nama-wholesale amukelekile.Siyakwamukela uku-oda kusuka ku-AASraw!

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Product Incazelo

1. I-Lorcaserin hydrochloride Powder Video-AASraw

 


2. Izinhlamvu eziyisisekelo ze-Lorcaserin hydrochloride Powder

Igama: Lorcaserin hydrochloride powder
CAS: 1431697-94-7
Ifomula Yamamolekhula: C11H15Cl2N
Isisindo Yamamolekhula: 232.1525
I-Melt Point: 212 ° C
Isitoreji Sokugcina: -20 ℃
Umbala: powder emhlophe

 


3. Umbiko Wokuhlola I-Lorcaserin hydrochloride eluhlaza-HNMR

I-Lorcaserin hydrochloride HNMR

Iyini i-HNMR futhi I-HNMR spectrum ikutshelani? H I-spectroscopy ye-Nuclear Magnetic Resonance (NMR) iyindlela yamakhemikhali yokuhlaziya esetshenziswa ekulawuleni ikhwalithi nokucwaninga ukuze kutholwe okuqukethwe nokuhlanzeka kwesampula kanye nesakhiwo salo samangqamuzana. Isibonelo, i-NMR ingahlaziya ngokwesilinganiso izingxube eziqukethe izinhlanganisela ezaziwayo. Ezihlanganisweni ezingaziwa, i-NMR ingasetshenziswa ukuze ifane nelabhulali ye-spectral noma ukucabangela isakhiwo esiyisisekelo ngokuqondile. Uma isakhiwo esiyisisekelo sesaziwa, i-NMR ingasetshenziswa ukunquma ukuhambisana kwamangqamuzana esixazululweni kanye nokufunda izici ezibonakalayo ezingeni lamangqamuzana njengokushintshisana kokuvumelana, izinguquko zesigaba, ukunyibilika, kanye nokusabalalisa.

4. Ini is Lorcaserin hydrochloride powder?

I-Lorcaserin hydrochloride iyi-hydrochloride etholakala ngokusabela kwe-lorcaserin nge-equilement eyodwa ye-hydrochloric acid. Isetshenziswa njengesidakamizwa esilwa nokukhuluphala. Inendima njenge-agonist ye-serotonergic kanye ne-depressant ye-appetite.

I-Lorcaserin hydrochloride powder ithinta izimpawu zamakhemikhali ebuchosheni obulawula ukudla. I-Lorcaserin HCL powder isebenza ngokukusiza uzizwe ugcwele ukudla okuncane.I-Lorcaserin hydrochloride powder isetshenziswa kanye nokudla nokuzivocavoca ukuze uphathe ukukhuluphala.I-Lorcaserin hydrochloride powder ngezinye izikhathi isetshenziselwa ukwelapha ukukhuluphala okungase kuhlotshaniswe nesifo sikashukela, i-cholesterol ephezulu, noma umfutho wegazi ophezulu. .

5. Iyini i-Lorcaserin hydrochloride enhle?

I-Lorcaserin hydrochloride isetshenziselwa ukusiza abantu abadala abakhuluphele ngokweqile noma abakhuluphele futhi abanezinkinga zezokwelapha ezihlobene nesisindo ukuze banciphise isisindo futhi bagweme ukubuyisela leso sisindo. I-Lorcaserin kumele isetshenziswe kanye nokudla kwekhalori encishisiwe kanye nohlelo lokuzivocavoca. I-Lorcaserin iseklasini lemithi ebizwa ngokuthi i-serotonin receptor agonists. Isebenza ngokwandisa imizwa yokusutha ukuze kudliwe ukudla okuncane.

I-Lorcaserin hydrochloride isetshenziswa kanye nokudla okuncishisiwe kwekhalori nokuzivocavoca okufanele ukukusiza ulahlekelwe isisindo. Ibuye isetshenziswe kubantu abakhuluphele okungenzeka nabo babe nesifo sikashukela, umfutho wegazi ophakeme, i-cholesterol ephezulu, noma isifo senhliziyo.

6. The Izinzuzo ze-Lorcaserin hydrochloride

I-Lorcaserin hydrochloride imithi elawulwa ngomlomo ekhuthaza ukulahlekelwa isisindo. Isetshenziswa ngokudla kanye nokuzivocavoca kubantu abadala abakhuluphele abanenkinga yezokwelapha ehlobene nesisindo noma abantu abadala abakhuluphele ukuze behlise isisindo futhi baqhubeke.

I-Lorcaserin hydrochloride iyi-agonist ye-serotonin 2C (5-HT2C). I-lorcaserin kucatshangwa ukuthi ikhuthaza ngokukhethekile i-5-HT2C receptors ku-hypothalamus, indawo yobuchopho eyaziwa ukuthi idlala indima enkulu ekulawuleni indlala nokudla ukudla. Ngokusebenzisa lawa ma-receptors, i-lorcaserin inganciphisa ukusetshenziswa kokudla ngokunciphisa isifiso sokudla nokwenza umuntu azizwe egcwele ngisho nangemva kokudla ukudla okuncane kunokujwayelekile.

I-Lorcaserin hydrochloride iyi-agonist ye-serotonin 2C receptor ekhonjiswe ekwelapheni ukuphathwa kwesisindo esingapheli kubantu abadala abane-index mass body (BMI) ye-30 noma ngaphezulu (okukhuluphele) njengesengezo ekudleni okuncishisiwe kwekhalori nokuzivocavoca. I-lorcaserin iphinde ivunyelwe ukuthi isetshenziswe ngabantu abadala abane-BMI ye-27 noma enkulu (i-overweight) futhi okungenani banesimo esisodwa esihlobene nesisindo njengomfutho wegazi ophezulu (umfutho wegazi ophezulu), uhlobo lwe-2 yesifo sikashukela, noma i-cholesterol ephezulu (dyslipidemia).

7. Lorcaserin hydrochloride esetshenziswa njengesidakamizwa esilwa nokukhuluphala ngokweqile

Ukukhuluphala kuyinto ebaluleke kakhulu empilweni edinga amasu aphephile nasebenzayo okubhekana nobhubhane lokukhuluphala. I-Lorcaserin iyi-agonist ye-serotonergic ethize ku-receptor ye-5HT-2C evunyelwe ukuphathwa okungapheli kokukhuluphala ezigulini ezine-BMI ≥ 30 kg / m (2) noma i-BMI ≥ 27 kg / m (2) ene-comorbidities ehlobene nokukhuluphala.

I-Lorcaserin iyi-agonist eyingqayizivele ekhethiwe kakhulu ye-serotonergic eyenzelwe ukunciphisa izingozi ezihlobene nama-agent wangaphambilini kuleli klasi. Ngemithamo yokwelapha, ibekezelelwa kahle futhi ikhiqiza ukuncipha kwesisindo okunesizotha kodwa okunenjongo ngokomtholampilo ngokuthuthuka okuphawulekayo kwemingcele ye-cardiometabolic. Ukuphumelela kokwelapha kufanele kuhlolwe emavikini angu-12 (≥ 5% ukuncipha kwesisindo) ukuze kuhlonzwe abaphenduli abazothola ukwehla kwesisindo esiphezulu kanye nenzuzo ye-metabolic ekwelapheni kwesikhathi eside. Imiphumela yocwaningo oluqhubekayo lwemiphumela ye-cardiovascular effects (CAMELLIA TIMI 61) izonquma indima ye-lorcaserin ekuvimbeleni okuyinhloko kwesifo sikashukela kubantu abakhuluphele / abakhuluphele kanye nokusetshenziswa kwayo kubantu abasengozini enkulu yeziguli ezinesifo senhliziyo esimisiwe noma izici eziningi eziyingozi zenhliziyo.

8. Ukuthenga kuphi Lorcaserin hydrochloride Impushana?

I-Lorcaserin isetshenziselwa ukusiza abantu abadala abakhuluphele noma abakhuluphele ngokweqile futhi abanezinkinga zezokwelapha ezihlobene nesisindo ukuze balahlekelwe isisindo futhi bagweme ukubuyisela emuva leso sisindo. I-Lorcaserin kumele isetshenziswe kanye nokudla kwekhalori encishisiwe kanye nohlelo lokuzivocavoca. I-Lorcaserin iseklasini lemithi ebizwa ngokuthi i-serotonin receptor agonists. Isebenza ngokwandisa imizwa yokusutha ukuze kudliwe ukudla okuncane.

9.Ireferensi

[1] Belviq (lorcaserin hydrochloride) tablet [Eisai, Inc]”. I-DailyMed. I-Eisai, Inc. Agasti 2012. Kufakwe kungobo yomlando kusukela kokwangempela ngomhla ka-21 Okthoba 2013. Kubuyiswe ngomhla ka-21 Okthoba 2013.

[2] "I-FDA icela ukuhoxiswa kwesidakamizwa esinciphisa isisindo i-Belviq, Belviq XR (lorcaserin) emakethe". I-US Food and Drug Administration (FDA). 14 Januwari 2020. Ibuyiselwe ngomhlaka-1 Ephreli 2020.

[3] “I-FDA Kafushane: I-FDA Icela Ukuhoxiswa Ngokuzithandela Komuthi Wokunciphisa Isisindo Ngemva Kokuhlolwa Komtholampilo Kubonisa Ukwanda Kwezehlakalo Zomdlavuza”. I-FDA. 13 February 2020.

[4] “I-Belviq XR (i-lorcaserin hydrochloride) amaphilisi okukhululwa okunwetshiwe”. I-US Food and Drug Administration (FDA). 26 Okthoba 2016. Ibuyiselwe ngomhla ka-14 Januwari 2020.

[5] “Iphakheji Yokuvunyelwa Kwezidakamizwa: I-Belviq (lorcaserin hydrochloride) Amathebulethi NDA #022529”. I-US Food and Drug Administration (FDA). 7 Agasti 2012. Ibuyiselwe ngomhla ka-14 Januwari 2020.

10. Indlela yokuthenga Lorcaserin hydrochloride I-Powder esuka ku-AASraw?

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