I-NMN powder - Umhlinzeki Wefektri Yomkhiqizi
I-AASraw ingumkhiqizi ochwepheshe we-anabolic steroid powder ngokulethwa okuphephile!

I-β-Nicotinamide Mononucleotide

Isilinganiselwa: Isigaba:

I-AASraw ineziqu zokunikezela ngemikhiqizo yokulwa nokuguga-i-NMN Powder ngobuningi ngomthethonqubo we-CGMP kanye nohlelo lokulawula ikhwalithi elandelekayo. Ukukhiqizwa kwethu okuphakathi nyangazonke kungafinyelela ku-1500kg. Siyakwamukela ukuxhumana nathi ukuthola eminye imininingwane yokuthenga:
Isimo: Kusesitokweni

Amaphakheji Unit: 1kg / isikhwama, 25kg / isigubhu

I-Quote esheshayo

Product Incazelo

Izici Eziyisisekelo

Igama Product β-Nicotinamide Mononucleotide (NMN)
CAS Inombolo 1094-61-7
Formula Yamamolekhula C11H15N2O8P
Isisindo sesisindo 334.22
omqondofana I-NMN;

β-D-NMN;

I-BETA-NMN;

i-beta-D-NMN;

I-NMN powder;

I-NMN zwitterion;

INICOTINAMIDE RIBOTIDE;

INicotinamide nucleotide;

I-nicotimide mononucleotide.

ukubukeka powder emhlophe
Isitoreji nokuphatha 2-8 ° C endaweni eyomile

Iphuzu eliyisihluthulelo:

I-NAD + i-coenzyme ebalulekile edingekayo empilweni nasemisebenzini yeselula.

♣ Amaleveli we-NAD +, ikakhulukazi ifomu lawo le-NAD +, lehla ngokwemvelo ngokukhula kwezicubu eziningi.

Body Umzimba udala i-NMN njengesinyathelo esiphakathi noma "umanduleli" we-NAD +. Kalula nje: amazinga aphezulu e-NMN asho amazinga aphezulu we-NAD +.

Kwaziwa: Kuma-athikili alandelayo, Kusetshenziswe i-NMN esikhundleni se-β-Nicotinamide Mononucleotide (NMN)


 

I-Nicotinamide Mononucleotide: Izinzuzo Nokusetshenziswa

Ukuguga kuyinqubo engokwemvelo engathinta impilo yakho ngokomzimba, ngokwengqondo nangokomzimba. Izimpawu zokuqala zokuguga zibonakala ebusweni nasentanyeni ngendlela yemigqa emihle nemibimbi. Imiphumela yezimonyo zokuguga ivame ukwengezelwa yizinto zangaphandle ezifana nokuvezwa kwe-UV okuholela esikhunjeni esenziwe isithombe kanye nengcindezi, ukukhathazeka, nokungcola kwemvelo okuvimba ama-pores okuholela ekucasukeni okungapheli kanye nezinduna. 

Le mibimbi imane nje iyisibonakaliso sezimonyo nesibonakala ngaphandle sokuguga kepha ngaphakathi, ingathinta ikhono lakho lokwenza imisebenzi yempilo yansuku zonke ngomdlandla namandla afanayo njengakuqala. Ngaphezu kwalokho, ukuguga kungathinta isisindo sakho kanye ne-metabolism, okuvame ukudala ukuzuza okungenampilo okuhambisana nesilinganiso se-basal metabolism esisheshayo. 

Izinguquko ezihambisana nokuguga azinakugwenywa ikakhulukazi ngoba ezinye zazo zingumphumela wokuncipha kwemetabolondrial metabolism kanye nezinguquko kusimo sezakhi zofuzo. Iningi lezinguquko zomzimba ezenzeka ngokuguga kungumphumela wamazinga we-NAD + anciphile, i-coenzyme ebalulekile ye-homeostasis kanye ne-metabolism etholakala kuzo zonke izinto eziphilayo. 

Ngesikhathi sobusha bethu, le coenzyme ibamba cishe kukho konke ukuphendula okukhiqiza amandla kwe-mitochondrial futhi itholakala kakhulu emzimbeni. Kodwa-ke, njengoba sikhula, amazinga we-NAD + aqala ukwehla kakhulu. 

Izithako zokulwa nokuguga zikhuthazwa kabanzi futhi zisetshenziswa ngabantu emhlabeni wonke ngethemba lokulwa nemiphumela yokuguga. Kodwa-ke, akuwona wonke asebenzayo njengoba iningi lawo lingathinti amazinga e-NAD + emzimbeni. Njengomphumela wezifundo eziningana. ososayensi nabaphenyi bathole isisombululo sokulwa nezimpawu zokuguga, isihluthulelo sempilo, okuyiNicotinamide Mononucleotide okuthi ngemuva nje kokusetshenziswa komlomo kuguquke kube yi-NAD + emzimbeni. 

 

Yini iNicotinamide Mononucleotide (NMN)? 

INicotinamide Mononucleotide iyi-nucleotide esuselwa ku-niacin noma i-vitamin B3 engatholakala futhi, njengoba kunjalo, kwizithelo nemifino ethile efana nama-avocado ne-edamame. I-NMN isanda kuthola ukubambeka njengokwengezelela ukulwa nokuguga, ikakhulukazi njengomphumela wokushicilelwa kwencwadi, i-Lifespan, nguDavid Sinclair.

I-NAD + yaziwa njengophawu lokuguga isikhashana kepha ukulwa nomphumela wokuguga emazingeni ayo bekunzima. Lokhu kungenxa yokuthi izifundo zokuqala zigxile ekwandiseni amazinga e-NAD + emzimbeni usebenzisa izithasiselo ze-NAD +. Kodwa-ke, kusheshe kwatholakala ukuthi i-NAD + inokutholakala okungekuhle emzimbeni okusho ukuthi ayitholi kalula, futhi ukuyidla ngokweqile akunamthelela emazingeni ayo endo native.

Isengezo seNMN siyisandulela esinamandla seNAD + esibalulekile kunqubo yokukhiqizwa kwamandla emzimbeni womuntu. Kodwa-ke, ucwaningo lokuqala ekusetshenzisweni kwe-NMN powder noma i-supplement njengesengezo sokulwa nokuguga lwenziwa kuphela ngonyaka we-2020. I-NMN isenendlela ende okufanele ihambe ezweni locwaningo kepha izifundo ezenziwe kuze kube manje zifakazele izinzuzo nemiphumela ye-NMN ekugugeni. 

Amaleveli we-NAD + angakhuphuka ngesinye sezandulela zayo ezimbili ezibalulekile, i-NMN njengoba kushiwo ngenhla noma i-NR. I-NMN ne-NR ziyahambisana, nokuguqulwa kwe-NMN ibe yi-NR kubaluleke kakhulu ekumungeni kowokuqala emzimbeni. I-NR imele iNicotinamide riboside engakhuphula kakhulu amazinga endo native NAD +. Ukwengezwa nge-NR ukulwa nemiphumela yokuguga kufundwe kahle ngezithasiselo ze-NR kumenyezelwa njengezithasiselo 'eziphephile nezibekezelelekayo'. 

 

Isebenza Kanjani I-NMN Emzimbeni?

I-NMN ibamba iqhaza elibalulekile enqubweni yokukhiqiza amandla nasekulungiseni i-DNA emzimbeni, yize ingaqondile. I-NMN ithuthukisa ukuhlanganiswa noma ukukhiqizwa kwe-NAD + emzimbeni ukuze kunqobe ukuntuleka kwayo, ngendlela yokuhlenga. I-NAD + ingahlanganiswa ngezindlela ezingaphezu kweyodwa futhi indlela yokulondoloza incike ekusebenzeni kahle kwe-NMN. Indlela ye-Salvage ibhekisa endleleni ekhiqiza i-NAD + ngemikhiqizo yokuphela kokuwohloka kwe-NAD + njenge-niacinamide noma i-NAM. I-NAM iguqukela ngqo ku-NMN okuthi lapho, ngezinyathelo ezahlukahlukene, ikhiqize i-NAD +. Lona umsebenzi obaluleke kunayo yonke we-NMN emzimbeni futhi yisona sizathu esikhulu sokwengeza ukuthandwa okwandayo kwe-NMN. 

Lapho usuthathe izithasiselo ze-NMN ngomlomo, kukholakala ukuthi ziguqulwa zibe yi-NR emzimbeni ngoba inhlanganisela yeNMN ayikwazi ukudlula kulwelwesi, iye kumaseli. Ngemuva kokuthi i-NR ingene esitokisini, ibuye iguqulwe ibuyele ku-NMN ngemiphumela ye-enzyme ethile; i-nicotinamide ribose kinase noma i-NRK. Le NMN ibese iqhubeka nendlela yokulondolozwa kwe-biosynthesis ye-NAD + ukugcwalisa amazinga akamuva emzimbeni womuntu. 

Kubalulekile ukuqaphela lapha ukuthi ukugcwaliswa kabusha kwe-NAD + nge-supplementation ye-NMN akugcini nje ngokuholela ekukhuphukeni kwamandla kepha futhi kunezinye izinzuzo zezempilo eziningi ezengeza kuphela kwisikhalazo sokwengezwa kwe-NMN. 

 

Izinzuzo Zezempilo ze-NMN

Izakhiwo ze-NMN zokulwa nokuguga akuyona nje imiphumela yamazinga akhuphukile we-NAD + kodwa futhi nomphumela wezindlela ze-NMN nemisebenzi emzimbeni womuntu. Inzuzo enkulu yeNMN namanje amandla ayo okukhulisa amandla eselula nawomzimba njengoba iyi-booster ye-NAD + kodwa, ezinye izinzuzo akufanele zinganakwa ikakhulukazi uma ubheka ukuthi ukwengeza kwe-NMN kuyisinqumo esifanele yini kuwe. 

Ukuba yi-NAD + booster kuvumela i-NMN ukuthi ikhiqize ezinye izinzuzo eziningi zezempilo, njenge:

 

· Ukuphathwa Kokukhuluphala

Izehlakalo zokukhuluphala ngokweqile zikhuphuke kakhulu kusukela eminyakeni engama-30 eyedlule, kanti iphesenti lokukhuluphala kwengane licishe laphindeka kabili kule minyaka engama-30. Lokhu kuyakhathaza ikakhulukazi ngoba ukukhuluphala ngokweqile kukubeka engxenyeni yezinye izinhlekelele ezingabulala. Izinga eliphansi lokunciphisa umzimba yisizathu esiyinhloko sokukhuluphala okuhlobene nobudala okuvame ukubonwa kubantu asebekhulile. Ukulawula lolu hlobo oluthile lokukhuluphala kudinga indlela yokwenza izinto eziningi ebhekise kuma-hormone endlala kanye namazinga we-metabolic. Ucwaningo olwenziwe eQatar luthole ukuthi ukwengezelwa kwe-NMN kumamodeli wezilwane kuholele ekwandisweni kwezakhi zofuzo zamahomoni amabili ayisihluthulelo ekunciphiseni ukudla nasekuhloleni imetabolism; i-leptin ne-sirtuin, ngokulandelana. Lolu cwaningo lukhombisa ukuthi ukungeniswa ngomlomo kwe-NMN kunganciphisa indlala ukukusiza wehlise isisindo ngenkathi futhi kukhulisa nezinga lokugaya ukudla, zombili lezo ezenza ihaba ukwehla kwesisindo ongase ubhekane nakho. 

Ngaphezu kwalokho, abacwaningi bathole ukuthi i-NMN inyusa amazinga e-NAD + kumaseli anamafutha anomthelela wokwandisa umzimba, nokuqhubeka nokusiza ekunciphiseni isisindo. 

 

· Ukulawulwa Kwesifo Sikashukela

Isifo sikashukela singenye yezinkinga zokukhuluphala futhi ukusebenzisa izithasiselo ze-NMN ukuphatha nokwelapha ukukhuluphala kungavimbela isifo sikashukela ukuthi sikhule. Kepha lokho akuwona ukuphela komphumela we-NMN emazingeni kashukela egazini. Kwehliswe amazinga e-NAD + atholakala ahlobene nokuncipha kokusebenza kwamaseli we-beta kumanyikwe, umthombo oyinhloko we-insulin emzimbeni. Abaphenyi bakholelwa ukuthi le yi-pathophysiology eyinhloko ngemuva kokuthuthukiswa kohlobo lwesifo sikashukela 2 kubantu abadala. 

Ucwaningo olwenziwe ezinhlobonhlobo zezilwane lubonise ukuthi amagundane onesifo sikashukela kanye nabadala, lapho enikezwa izithasiselo ze-NMN, ayenze ngcono ukusebenza kwe-beta-cell njengoba igcwalisa izitolo ze-NAD + emzimbeni. Olunye ucwaningo lwalugxile ekutholeni umgomo wokwelashwa wesifo sikashukela sohlobo lwesifo sikashukela esihlobene nobudala kanye nokukhuluphala ngokweqile sathola ukuthi izengezo ze-NMN zazinamandla okuthinta isibindi futhi zenyuse uketshezi okwenziwe ngamafutha. Zinganciphisa nokugcinwa kwamafutha emzimbeni ngenkathi zithuthukisa nokubekezelelana kwe-glucose emzimbeni. 

Izithasiselo ze-NMN zinezindlela eziningana ezisiza ngazo ukwenza ngcono ukubekezelelana kwe-glucose kanye nokumelana ne-insulin, ngaleyo ndlela kusize ukuphatha uhlobo lwesifo sikashukela se-2 kubantu asebekhulile. Izindlela ezifanayo zisetshenziselwa ukunciphisa ngempumelelo izimpawu zokunye ukuphazamiseka kwemetabolism okuthuthuka ngenkathi yenqubo yokuguga. 

 

· Umsebenzi Okhuphukile Wamasosha Omzimba

Njengoba kunikezwe ukuthi ukwesekwa nge-NMN muva nje kube yindlela esebenzayo ecwaningwe, okungenani kumamodeli ezilwane, akumangazi ukuthi indima ye-NMN yafundwa maqondana nokutheleleka nge-COVID-19. 

Ngenkathi befunda izindima ezahlukahlukene ze-coenzyme enhlobonhlobo, i-NAD +, abacwaningi bathole ukuthi ibamba iqhaza elibalulekile ekusebenzeni kahle kohlelo lomzimba. Ubhadane lwakamuva lwe-COVID-19 lududule abacwaningi ukuthi bafunde ukuxhumana okuqondile phakathi kwezithasiselo ze-NMN, kwandise i-NAD +, kanye nokusebenza komzimba okuthuthukisiwe ukulwa nemiphumela yegciwane. 

Olunye ucwaningo olunjalo lwathola ukuthi amazinga we-NAD + aphelile futhi kamuva, ukukhula kweminyaka, okuholela ezinhlotsheni ezinzima zokutheleleka. Kutholakale nokuthi lezi ziguli zisengozini enkulu yokuhlaselwa komzimba nokufa ngenxa yokutheleleka nge-COVID-19. Njengomphumela walokhu okutholakele, kungacatshangwa ukuthi ukwengezwa kwe-NMN kungakwazi ukwehlisa ubunzima i-COVID-19 ethinta ngayo amasosha omzimba nomzimba womuntu. 

 

· Ukuzala Kwabesifazane Okuthuthukisiwe

Abesifazane bathintwa yiwashi lezinto eziphilayo elikhawulela amakhono abo okuzala ngobudala. Izifundo ezahlukahlukene ezenziwa ezinhlobonhlobo zezilwane zesifazane zithole ukuthi ukwengezelwa kwe-NMN kungakwazi ukunciphisa le mikhawulo futhi kulaphe ukungabi nenzalo okuhambisana nobudala kwezinye izimo. 

Ucwaningo olwenziwe kumagundane asebekhulile ngokwemvelo, abesifazane bathola ukuthi ukwehla kwamazinga e-NAD + kungaholela ekwehliseni ikhwalithi ye-oocyte kanye nokwehla okuphawulekayo kwezinombolo ze-oocyte, okunciphisa ikhono lokuzala nokuzala. Ukubuyisela amazinga e-NAD + kulezi zinhlobo zezilwane nge-NMN supplementation kutholakale ukukhulisa ikhwalithi ye-oocyte nezinombolo zayo, yingakho kuthuthukiswa ikhono lokukhiqiza kabusha. 

Olunye ucwaningo lwenziwa ukuhlola ngqo ukuthi yini enciphisa ikhwalithi yama-oocyte aneminyaka yobudala. Kulolu cwaningo, ama-oocyte avela kwabesifazane asebekhulile aqoqwa futhi afundwa, ngokujulile ukuqonda i-pathophysiology. Abaphenyi bathola ukuthi ukwehla kwekhwalithi ye-oocyte kwakuwumphumela wokuguqulwa kwamaphoyinti ku-DNA ye-mitochondrial ye-oocyte, ekhula ngenxa yokungalingani kwamazinga e-NAD +. Kungakho ukuxhaswa kwe-NMN ukukhuphula amazinga e-NAD + kukholakala ukuthi kuthuthukisa impilo yokuzala kanye nokuzala, ikakhulukazi kwabesifazane asebekhulile. 

Njengoba abesifazane asebekhulile belahlekelwa iningi lamakhono abo okuzala ngesikhathi sokunqamuka kokuya esikhathini, izengezo ze-NMN, kanye nokukwazi ukuthuthukisa impilo yokuzala nakho kungakwazi ukuguqula ukuya esikhathini, ngezinga elithile. Lokhu kuzovumela abesifazane ukuthi bavunde isikhathi eside futhi babe nekhwalithi ephezulu yama-oocyte noma ngabe seqe umkhawulo wobudala ojwayelekile. 

 

· Ukwanda Kokugeleza Kwegazi

Ngokuya ngocwaningo olwenziwe nguDkt DAvid Sinclair, isazi sebhayoloji esibhekele udumo lwezithasiselo ze-NMN, njengoba sikhula, amaseli endothelial anemithambo yegazi ancipha ngenani nekhwalithi. Lokhu-ke kuthinta izakhamzimba ezidlula zisuka egazini ziye ezicutshini lapho kudlula khona izitsha, yingakho kuthinta ikhwalithi yonke yomkhumbi wegazi. Lezi zinguquko kukholakala ukuthi yizona ezibangela ukwanda kwezigameko zokugula kwemithambo yegazi kubantu asebekhulile.

Ukwengezwa kwe-NMN noma ukwengezelwa kwe-NR kubangela ukukhuphuka kwamazinga e-NAD +, okuthi ngokwalolu cwaningo kubangele ukuthi amaseli endothelial asebenze futhi abe namandla okukhiqiza imithambo yegazi emisha lapho endala iyeka ukusebenza kahle. 

 

· Umsebenzi Wokuqonda Othuthukisiwe

Izinkinga ze-Neurodegenerative yizinkinga ezivamile ezithinta ubuchopho, ukwehla kokusebenza kwengqondo kanye nekhwalithi yempilo. Ukwengezwa nge-NMN ukukhuphula amazinga e-NAD + kukholakala ukuthi kusebenza kakhulu ekuthuthukiseni ukusebenza kwengqondo nokuthuthukisa ukusinda kwamaseli obuchopho. 

Esifundweni lapho onobuhle bezilwane abanokulimala kwengqondo okuhlukumezekile kanye ne-neurodegeneration banikezwa inhlanganisela ethile,  I-P7C3-A20, kutholakale ukuthi le nhlanganisela yathuthukisa umsebenzi wokuqonda futhi yamisa izinqubo ze-neurodegenerative. 

I-P7C3-A20 iyinhlanganisela ekhiqiza i-NMN ebese ikhiqiza i-NAD +. Ukunikeza amagundane nge-TBI le nhlanganisela kwatholakala ukuthi ayinazo izinzuzo zokuqonda kuphela kepha futhi yatholwa ikhulisa ubuqotho bokusebenza nokwakheka kwesithiyo segazi nobuchopho, njengoba le nhlanganisela iyingxenye yolwelwesi. 

 

· Umsebenzi Othuthukile Wemisipha Nokukhuthazela Okwengeziwe

Abasubathi abangathanda ukuthuthukisa amakhono abo okukhuthazela kufanele bathathe izithasiselo ze-NMN njengoba kusanda kutholakala ukuthi lezi zithasiselo zinamandla okuthuthukisa amandla azo e-aerobic. Le nzuzo yezengezo ze-NMN ikakhulu ngenxa yomphumela wokukhiqizwa kwamandla we-NAD + emisipheni, kepha kubalulekile ukuqaphela ukuthi laba basubathi nabo bathola ukwanda okuphawulekayo emazingeni okuthatha imisipha yabo yemisipha.  

 

Ingabe kufanele ngithathe i-NMN Powder?

I-NMN Powder inezinzuzo eziningana ezifundwe ngokuningiliziwe, kumamodeli ezilwane nase-laboratory. Ezinye zalezi zinzuzo zifundwe ngabantu, futhi zaveza imiphumela emihle. Uma uqala ukubona izimpawu zokuguga noma ngabe zingendlela yokwehla kokubekezela, amakhono ezemidlalo, noma izimpawu zezimonyo, ungazuza ngokuthatha izithasiselo ze-NMN. Ukusetshenziswa kwabo kunconywa ikakhulukazi kulabo abazama ukuguqula izimpawu zokuguga. 

 

Izingozi Ezingaba khona zeNMN

I-NMN iyinhlanganisela etholakala ngokwemvelo emzimbeni womuntu, ukuthi ngemuva kocwaningo olunzulu nokuhlaziywa kwatholakala ukuthi akunabo ubungozi noma izinkinga ezihambisana nakho. I-NMN, lapho yenziwe kahle ngumhlinzeki weNMN futhi igcinwa kahle efektri ye-NMN powder nasekhaya lakho, iphephe ngokuphelele ukusetshenziswa kwabantu. Ukugcinwa kwempuphu yeNMN kubalulekile ngoba uma igcinwe endaweni eshisayo, izophenduka i-niacinamide bese iqala ukufaka ushevu emzimbeni wakho kancane uma uyisebenzisa. 

Akudingeki ukhathazeke njengoba i-NMN powder emsulwa yenkampani yeNMN igcinwa njalo ngokufanele, endaweni ebandayo neyomile. Ngaphezu kwalokho, abakhiqizi be-NMN powder baphinde baphrinte izinkomba eziqondile zokusetshenziswa nokugcinwa ekupakisheni izithasiselo ukuze wazi ukuthi uzisebenzisa kanjani kangcono, ngaphandle kokuholela ezinkingeni ezinzima. 

Kubalulekile futhi ukuqaphela ukuthi ukusetshenziswa njalo kwezithasiselo ze-NMN kungaholela ekwehleni kwekhono lezithasiselo ukukhiqiza imiphumela oyifunayo. Ngalesi sizathu, kunconywa ukuthi uthathe ikhefu kokunezelwa lapho uqala ukubona izinzuzo ze-NMN ezinciphile njengezinga lokuncipha lokulala nokwanda kwezifo. 

Ngokuphathelene nokunakekelwa okufanele kuthathwa ngesikhathi senqubo yokukhiqiza nokugcina, kokubili ekhaya nasefektri, azikho izingozi nemiphumela emibi ehlotshaniswa nokusetshenziswa kwe-NMN. 

 

Ungawuthengaphi Powder ohamba phambili weNMN?

Ungathenga i-NMN powder kanye nezinye izinhlobo zezengezo ze-NMN kuma-pharmacy aku-inthanethi, ezitolo zezempilo, kanye nozakwabo bendawo. Ungathenga nezikhwama zenqwaba ye-NMN powder equkethe inani elikhulu lempuphu ye-NMN, yize kuyizinga lezimboni futhi livame ukuthengwa izinkampani ezinkulu ezizama ukwenza amaphilisi namaphilisi we-NMN. 

Ungathenga futhi i-NMN powder evela e-Amazon noma e-Amazon Prime, kepha kufanele uqaphele ukuthenga umkhiqizo wangempela kubathengisi abaqinisekisiwe njengoba abathengisi abaningi abangahleliwe bangakukhohlisa ukuthi ukhokhe inani elikhulu le-dupe noma i-fake, lokho okungenamthelela kukho impilo yakho noma iba nomthelela omubi empilweni yakho. 

Ngaphambi kokuqala ukuthenga i-NMN powder, kufanele uhlole izinto ezimbalwa ukuqinisekisa ukuthi uthenga umkhiqizo omuhle kakhulu kuwe. 

Isengezo esihle kakhulu se-NMN yilokho okwenziwa ngayo yonke imihlahlandlela yokuphepha kanye nezivumelwano ezikhona. Abahlinzeki be-NMN kufanele baqinisekise ukuthi kunakwa kakhulu ukuvimbela ukungcoliswa kwempuphu ye-NMN nganoma yikuphi ubuthi noma ukungcola okungadala umonakalo omkhulu kunokulunga emzimbeni womuntu. 

Ngaphezu kwalokho, i-powder ye-NMN kufanele, njengoba kushiwo ngenhla, kufanele igcinwe ezimeni ezifanele futhi okufanele zigcinwe ngenkathi kuthuthwa izithasiselo. 

 

I-FAQ Mayelana ne-NMN Powder

· Ngabe i-NMN powder ingaguqula ukuguga?

I-NMN powder ikhangiswa njengesengezo sokulwa nokuguga futhi kufanele, ngoba inyusa amazinga e-NAD + adlala indima ebalulekile ekwehliseni amazinga akho wamandla njengoba ukhula. Akugcini lapho, i-NMN powder ingaguqula imiphumela yokuguga ezinhlelweni ezahlukahlukene zomzimba wakho, ikubuyisele ezinsukwini zakho zobusha, ezinamandla. 

 

· Ingabe i-NMN powder iphephile? 

I-NMN powder icwaningwe kahle ukuhlola imisebenzi ehlukene nezinzuzo ukusetshenziswa kwayo okungaba nayo emzimbeni womuntu. Ngesikhathi salezi zifundo, imiphumela emibi engaba khona nayo yahlaziywa kuphela ukuze imiphumela ikhombise ukuthi ukusetshenziswa kwe-NMN akunayo imiphumela emibi ehambisana nakho. Noma iyiphi inkinga engenzeka ngokusetshenziswa kwe-NMN powder kungumphumela wephutha lomuntu noma lobufundisi elenziwa ngesikhathi sokuhamba noma sokugcinwa. Akukho nokukodwa okuhlobene nesithako sangempela sesengezo sokulwa nokuguga. 

 

· Ibiza malini i-NMN powder?

I-NMN powder iyisengezo esitholakala kalula futhi esimba eqolo kodwa kubhekwa njengokufanele, uma unikezwa uhlu lwayo olukhulu lwezinzuzo eziqinisekiswe ngokwesayensi. Intengo ephezulu ye-NMN powder ayibangelwa uhlu olude lwezinzuzo kepha kunomphumela wenqubo yokukhiqiza ebanzi kakhulu yona uqobo ebiza kakhulu kubakhiqizi abaningi be-NMN. Ngokunikezwa kwemvelo ebizayo yesengezo, kufanele uqinisekise njalo ukuthi uthenga umkhiqizo wangempela kubathengisi abaqinisekisiwe, ikakhulukazi uma uthenga i-NMN online.

 

Isifinyezo

Izithasiselo ze-NMN ziya ngokuya zithandwa kakhulu ngosuku, ngenxa yomsebenzi wesazi sezinto eziphilayo uDavid Sinclair osebenzise nengxenye enkulu yomsebenzi wakhe wokucwaninga izifundo futhi efunda ngemiphumela yale vithamini B3 etholakala nge-nucleotide.

I-NMN iyisandulela se-NAD + eyi-coenzyme edingekayo ekusebenzeni okufanele kwezindlela eziningana ze-metabolic, immune, ne-hormonal. Umsebenzi omkhulu we-NAD + yiqhaza eliyidlalayo enqubeni yokukhiqiza amandla. Njengoba i-NAD + ibalulekile ekukhiqizweni kwamandla, ukwehla komzimba emazingeni ayo njengoba iminyaka yobudala eyodwa ibangela ukuncipha okuphawulekayo kwamazinga kagesi. Ukwengeza kwe-NMN kungasiza ukukhulisa amandla ngokukhulisa amazinga we-NAD + emzimbeni. 

I-NMN ibuye ibe nezinye izinzuzo eziningana njengokuthuthukisa ukusebenza komzimba, ukuthuthukisa ukusebenza kwenhliziyo, ukuqonda, ukujikeleza kwegazi, kanye namasosha omzimba. Le misebenzi isekelwa ubufakazi besayensi nedatha, efuna ukusetshenziswa kabanzi kokungezelelwa kwe-NMN kubantu asebekhulile ukubasiza isikhathi sokubuyela emuva ezinsukwini zabo zobusha. 

Ngaphandle kwezinzuzo ezimbalwa ze-NMN, ukuthandwa kwayo kungabizwa ngokuthi ayinazo izingozi ezinkulu noma izinkinga ezihambisana nokusetshenziswa kwayo. Uma uzizwa iminyaka yakho ikufica futhi ungathanda isiphuzo esiphuma emthonjeni wobusha, izengezo zeNMN kungaba ukukhetha okuhle kuwe. 

 

Izikhombo

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[2] UStipp D (Mashi 11, 2015). "Beyond Resveratrol: I-Anti-Aging NAD Fad". Inethiwekhi Yesayensi YamaMelika.

[3] ICambronne XA, iKraus WL (Okthoba 2020). "+ Synthesis kanye nemisebenzi Amaseli Mammalian". Amathrendi ku-Biochemical Sciences. 45 (10): 858-873. i-doi: 10.1016 / j.tibs.2020.05.010. PMC 7502477. PMID 32595066.

[4] UBogan KL, uBrenner C (2008). "I-Nicotinic acid, i-nicotinamide, ne-nicotinamide riboside: ukuhlolwa kwamangqamuzana ama-NAD + amavithamini angaphambi kokudla komuntu". Ukubuyekezwa Kwaminyaka Yonke Kwezomsoco. 28: 115-30. i-doi: 10.1146 / annurev.nutr.28.061807.155443. I-PMID 18429699.

[5] Yue Yang, Anthony A. Sauve. I-NAD + metabolism: Bioenergetics, signaling and manipulation for therapy. I-Biochim Biophys Acta, 2016; INGXENYE: 10.1016 / j.bbapap.2016.06.014.

[6] Izigayo KF, Yoshida S, Stein LR, Grozio A, Kubota S, Sasaki Y, Redpath P, Migaud ME, Apte RS, Uchida K, Yoshino J, Imai SI. Ukuphathwa Kwesikhathi Eside kweNicotinamide Mononucleotide Kunciphisa Ukwehla Kwemvelo Okuhambisana Nobudala Emagundeni. Iseli Metab, 2016; INGXENYE: 10.1016 / j.cmet.2016.09.013.

[7] UNiels J. Connell, uRiekelt H. Houtkooper, uPatrick Schrauwen. I-NAD + metabolism njengelitshe lempilo ye-metabolic: siyitholile yini inhlamvu yesiliva? Isifo sikashukela, 2019; INGXENYE: 10.1007 / s00125-019-4831-3.

[8] U-Ann Katrin-Hopp, uPatrick Grüter, uMichael O. Hottiger. Ukulawulwa kweGlucose Metabolism yi-NAD + ne-ADP-Ribosylation. Amaseli, 2019; I-DOI: 10.3390 / amaseli8080890.

[9] UShuang Zhou, uXiaoqiang Tang, uHou-Zao Chen. Ama-Sirtuins nokuphikiswa kwe-Insulin. Ngaphambili Endocrinol (Lausanne), 2018; INGXENYE: 10.3389 / fendo.2018.00748.