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Ngabe u-Orlistat Usebenza Kanjani Njengomuthi We-Light Loss

Ngokusho kwedatha evela kuWorld Population Review, i-United States isezingeni le-12 emhlabeni wonke ngenxa yokukhuluphala kwabantu bakhona. ICentre for Disease Control (CDC) ilinganisela ukuthi ama-36.9% abantu abadala baseMelika abaneminyaka yobudala engama-20 baneminyaka yobudala obukhulu, ngokususelwa kwimininingwane eqoqwe ngonyaka we-2016.

Izibalo ezisemthethweni zikhombisa ukuthi ama-41.1% abesifazane, kanye nama-37.9% amadoda - noma ngaphezulu kwamaMelika ayizigidi ezingama-160, alwa nokukhuluphala. Izibalo zamanje zikhombisa ukuphindwe kabili kokukhuluphala kwabantu baseMelika kuleminyaka engamashumi amathathu edlule.

Ngeshwa, imininingwane ayibukeki ingcono kakhulu kwentsha yaseMelika, noma. Cishe i-15% yabo bonke abasha nezingane zikhuluphele noma zikhuluphele, okuyinto ephindwe kathathu uma iqhathaniswa ne-1980s.

Ngokwemininingwane evela kwi-The State of Obesity, idatha yakamuva evela ku-Behavioral Risk Factor Surveillance System (BRFSS), ikhombisa ukuthi izifundazwe eziyisishiyagalolunye zinamazinga okukhuluphala angaphezu kuka-35%. I-Kansas, iFlorida, iNew Mexico, i-Utah, iMissouri, iMinnesota neNew York bonke babona amazinga okukhuluphala enyuka kubantu abadala nasezinganeni phakathi kuka-2017 no-2018. (1,2)

Ngakho-ke, kungani iMelika ibhekene nobhubhane lokukhuluphala oluthinta abantu abadala nezingane ezweni lonke? Ukhuluphala kunezixhumanisi eziqinile zokukhetha indlela yokuphila engemihle nemikhuba yokudla. Izingane zidlala ngaphandle kakhulu kunangaphambili ngeminyaka yama-1980s, ngentuthuko kwezobuchwepheshe zokwethula imidlalo yevidiyo kanye nezinye izindlela zokuzijabulisa ezigcina izingane zihlala phansi.

Abantu abadala banezinsizakalo zokuzijabulisa nezokulethwa kokudla okutholakala kalula ngezikhathi zewashi. Konke ukusebenziseka okwengeziwe ezimpilweni zethu kunezela ekusetshenzisweni ngokweqile kwama-kilojoule, futhi hhayi ukuzivocavoca okwanele kokushisa amandla atholakalayo.

Ukudla amakhalori amaningi ngokwezidingo zakho zamandla kuholela emzimbeni, kugcina amandla asele njengamafutha. Ukukhetha kabi kwendlela yokuphila, ukudla okune-calorie-dense okunamafutha amaningi kanye namafutha amabi, futhi akukho lutho ukuzivivinya, kuyindlela yokuthola ukukhuluphala - Konke okudingayo isikhathi.

1. Yini i-Orlistat?

Ukukhuluphala ngokweqile kunciphisa izinga lempilo yomuntu othintekile. Kodwa-ke, ngenkathi iningi labantu baseMelika libona ukuthi ukukhuluphala ngokweqile kungayilimaza impilo yabo, bambalwa kakhulu abathatha isinqumo sokwenza okuthile ukuyekisa ukuthuthuka kwabo ekukhuluphisweni.

Iningi labantu abakhuluphele ngokweqile nabakhuluphele abanalo ulwazi nesiyalo esidingekayo ukwenza ukuguqulwa komzimba noma ukudla okunciphisa umzimba. Kulabo abaqala ukuguqulwa komzimba, abangaphansi kwama-5% bayakwazi ukufeza isisindo somgomo wabo.

Iqiniso ngukuthi ukulahlekelwa amafutha omzimba ngokweqile lapho ukhuluphele ngokweqile noma ukukhuluphala kuyinselelo okubonakala kunzima ukukunqoba. Ukushintsha izindlela zokuphila, ukuguqula indlela odla ngayo, nokuqala uhlelo lokuzivocavoca kudinga inani elithile lokuzinikela egameni lomuntu onamafutha.

Ngaphandle kokuholwa nokuphefumulelwa, umuntu omningi ulahlekelwe ugqozi ngokuguqulwa komzimba wakhe, okubenza babuye imikhuba elimazayo.

Inqubekela phambili kwisayensi yokudla okunempilo eminyakeni engama-20 eyedlule ikhiqize ezinye izindlela ezithokozisayo nezijabulisayo ezixazululweni zamakhemikhali ukulawula nokuphulukisa ukukhuluphala. “I-grail engcwele” yocwaningo lwe-pharma ukwenza iphilisi lokunciphisa isisindo elivumela abantu abakhuluphele ukuthi babuyisele imizimba yabo kwi-BMI enempilo.

Ungase uzithole usungabaza kwanoma yimuphi umondli noma udokotela okutshela ukuthi kunepilisi elifanele lokunciphisa isisindo lokukhuluphala.

I-Orlistat, ngenye indlela eyaziwa ngamagama ayo ohlobo lwe-Alli ne-Xenical, inamandla okuba isidakamizwa sokulahlekelwa isisindo esinikeza abantu abakhuluphele ithuba lokubuyisela imizimba yabo empilweni.

Abantu abakhuluphele ngokweqile bangathenga i-Orlistat ngaphezulu kwekhawunta ku-60mg (Alli). Uhlobo lwe-120mg (Xenical), ludinga umuthi kadokotela wokuthenga nokusetshenziswa. Kunezinhlobo eziningi zohlobo olujwayelekile ezitholakala online.

I-Orlistat iyisidakamizwa esenzelwe ukulekelela uhlelo lokudla nokuzivocavoca lomuntu ngamunye. Ngakho-ke, asikwazi ukuyibiza ngokuthi yipilisi yokulahlekelwa isisindo esiyisimangaliso, ngoba isadinga umsebenzisi ukuthi enze umzamo othile ekudleni kwabo nasekuzivocavoca.

Kodwa-ke, imibiko yabasebenzisi iphakamisa ukuthi i-Orlistat iyisidakamizwa esisebenza kakhulu sokusheshisa isisindo lapho iphathwe kanye nezinkombandlela ezifanele zokudla okunempilo nezokuzivocavoca kwezidingo zomuntu omningi ngokweqile.

Abantu abadala abaneminyaka yobudala ephakathi kweyi-18 ubudala bangathenga amaphilisi we-60mg Orlistat ngaphezulu kwekhawunta, inqobo nje uma benama-body Mass Index (BMI) angama-25 noma ngaphezulu. Abantu abakhuluphele ngokweqile abane-BMI engaphezu kwama-30 bangavakashela udokotela wabo ukuthola umuthi wamathebhulethi we-120mg Orlistat ongawasebenzisa ndawonye ukunciphisa isisindo sokudla.

Odokotela bangavuma futhi ukusetshenziswa kwenguqulo ye-120mg kubantu abane-BMI abangaphansi kwama-27, uma bebhekene nezinye izinkinga zempilo, ezinjengoshukela noma umfutho wegazi ophakeme. Labo bantu abasebenzisa i-Orlistat ngaphansi kokuqashwa kukachwepheshe wezokwelapha bangafaka isicelo sokuthi umshuwalense wabo ukhokhe izindleko zomuthi.

Kodwa-ke, akubona bonke abomshuwalense abangabopha ukwelashwa. Ukuthola umhlinzeki we-Orlistat ku-inthanethi kulula kakhulu, futhi imihlahlandlela yentengo ye-Orlistat yabathengisi abakwi-inthanethi iyahlukahluka, kuya ngedumela nekhwalithi.

Ngakho-ke, u-Orlistat usebenza kanjani?

I-Orlistat ivimba ipheshana le-GI ekutholeni amanoni ekudleni okudingayo. Ngenxa yalokhu, amafutha angenakuphikiswa ekudleni kwakho adlula ngohlelo lwakho lwesisu, lapho umzimba uwudlula khona ngendaba eyinqaba.

Ama-carbohydrate namaprotheni aqukethe ama-kilojoule angama-4 wamandla kuyo yonke igramu. Noma kunjalo, igramu yamafutha iqukethe ama-9-calories. Ngakho-ke, umqondo ngemuva kwe ukusetshenziswa kwe-Orlistat ukuvikela abantu abakhuluphele ekutholeni lokhu kudla okune-calorie-dense.

Abantu abakhuluphele ngokujwayelekile badla ukudla okunamafutha amaningi, futhi ukukhetha kwabo ukudla akunampilo. Ngokunqanda umthamo we-caloric futhi uguqule ekudleni komuntu okhuluphele ekukhetheni okunempilo, umuntu okhuluphele ngokweqile uzoqala ukubona imiphumela masonto onke kuya kweviki ekuguqulweni kwemizimba yabo.

Kodwa-ke, abantu abakhuluphele ngokweqile bangathatha iminyaka emi-3 kuye kwemi-5 yokuzibophezela ekuguqukeni kokudla, ukuzivocavoca nezindlela zokuphila, ngaphambi kokuba babuyela kwi-BMI enempilo.

Ukuhlala sigxilile oguqukweni lokulahlekelwa isisindo salobukhulu kuyinselele kunoma yimuphi umuntu. Ngakho-ke, abantu abakhuluphele ngokweqile bangakwazi ukufaka uhlelo lwabo lokudla nokuzivocavoca nokusebenzisa i-Orlistat ukusheshisa imiphumela.

Ngabe u-Orlistat Usebenza Kanjani Njengomuthi We-Light Loss

2. Ingabe i-Orlistat ivunyelwe njenge ephephile ukuze isetshenziswe yi-FDA?

Njenganoma yisiphi isidakamizwa, i-Orlistat idlule ekuhlaziyeni nasekuhlolweni kwe-FDA ngokucophelela. Ukuvunywa kwe-Orlistat FDA kudlule ngo-1999 ngaphansi kwenombolo ye-CAS 96829-58-2.

I-FDA yahlola izinhlobo zomkhiqizo ezinhlolweni zomtholampilo ngo-1999, ivumela inguqulo ye-Xenical yemithi efanelekile ukusetshenziswa kanye nokuholwa ngudokotela oqeqeshiwe wezokwelapha. Kodwa-ke, kubalulekile ukuthi uqaphele ukuthi i-Xenical itholakala kuphela ngaphansi kadokotela.

I-FDA igunyaze u-Alli (60mg Orlistat) njengokuphephile ukuthi isetshenziswe kubantu abakhuluphele ngaphezulu kweminyaka engu-18 ubudala. Noma kunjalo, inguqulo ye-60mg iyatholakala ukuthi ithengwe ngaphezulu kwekhawuntara. Ngenkathi uhlobo lwe-OTC lusetshenziswa kuphela ngokudla okukhawulelwe kokhalori, okunamafutha aphansi, abukho ubufakazi obuphathekayo bokuholwa okudingekayo lapho abantu abakhuluphele ngokweqile Thenga i-Orlistat phezu kwekhawunta.

I-FDA ilandelela yonke imibiko yemiphumela emibi kubasebenzisi be-Alli ne-Xenical, izinhlobo zomkhiqizo ze-Orlistat. Le nhlangano ithole izinkulungwane zezaziso ezivela kubasebenzisi maqondana nemiphumela emibi nezehlakalo ezingezinhle ezenzeka ngesikhathi kusetshenziswa umuthi.

Ngale mibiko eminingi engemihle yezempilo, kungesabisa abanye abasebenzisi abangahle babe kude nokuyifaka kuhlelo lokunciphisa umzimba. Kodwa-ke, iqiniso ukuthi izehlakalo ezimbi zempilo ezibikwe ku-FDA ngumphakathi, zenziwa kuphela nge-Alli neXenical, hhayi i-Orlistat ngokuqondile.

Kuze kube manje, abukho ubufakazi bemitholampilo obuphakamisa ukuthi u-Orlistat unesibopho semicimbi yezempilo engemihle etholwa ngabasebenzisi baka-Alli nabama-Xenical. Kungenzeka ngokuphelele ukuthi lezi zinkinga zingaqhamuka kwesinye isithako esisetshenziswe ekwenziweni kwomuthi.

I-FDA iyaqhubeka nokuphenya imiphumela emibi nezinkinga ngobuthi ezungeze ukusetshenziswa kwe-Alli ne-Xenical. Kodwa-ke, kusamele sikhiphe noma yisiphi isitatimende esiphathelene nokuqeda ukuphepha nokuvunywa kwemithi.

I-FDA iphinde ibe nokukhathazeka okuthile mayelana nokuthi ithola imibiko kusilinganiso esisodwa kuphela kweziyishumi ezimbi. Le nhlangano iphinde yaqhuba izivivinyo ngobungozi besibindi se-Alli kubasebenzisi ngo-1.

Izilingo zifaka ukuhlaziywa kwe-datha yangaphambi kokuya ekliniki, emtholampilo, ngemuva kokuthengisa, kanye nokusetshenziswa kwezidakamizwa okuhambisana nokuqina kwesibindi kanye nokulimala ngenxa yokusebenzisa umuthi we-Xenical branded. (3)

Imiphumela yocwaningo iphetha ngokuthi iXenical ayixhumeki ekwakheni ubuthi obunamandla besibindi noma ukulimala.

Kodwa-ke, i-FDA iveze amacala ayi-12 ekuhlaziyeni kwemakethe okuhlobene nokulimala kwesibindi okubangelwa iXenical, nelilodwa ngokusetshenziswa kwe-Alli. Ukuqhubeka nokucwaninga kobufakazi kukhombisa ukuthi ezinye izinto ezinomthelela, njengokuphelelwa ngamanzi emzimbeni, kanye nokusebenzisa i-off-label noma ukusetshenziswa kwezidakamizwa, zingaba imbangela yokulimala kwesibindi okukhulu kulezi zimo. (4)

3. I-Orlistat njenge-Weight Loss Drug

Ngokuzayo lapho uhamba ezansi kwendlela yesengezo eGNC yangakini, bheka isigaba sokulahleka kwamafutha. Uzothola inqwaba yemikhiqizo yokunciphisa isisindo emandleni nasendleleni yepilisi. The isisindo sokulahlekelwa kwesisindo ibhizinisi imboni yamadola ayizigidigidi, futhi kunenqwaba yemikhiqizo ezama ukubusa lesi sikhala.

Kubalulekile ukuqaphela ukuthi i-Orlistat isidakamizwa sokulahlekelwa isisindo, hhayi isengezo sokunciphisa umzimba. Uma uthatha izithako eziningi zokuncipha kwesisindo, ungathola imiphumela emincane ethambile ye-thermogenic, efana nesisu esibuhlungu noma ukwanda okuncane kokunyusa nokushisa.

Kodwa-ke, ukusetshenziswa kabi noma ukuhlukunyezwa kosokhemisi isisindo somzimba, njenge-Orlistat, kungahle kube nemiphumela emibi emibi engathinta inhlala-kahle yakho isikhathi eside.

I-Orlistat isebenza kahle, futhi abanye abasebenzisi banganquma ukukhulisa iphrothokholi yabo yokuthuthukisa imiphumela yabo. Kodwa-ke, leliqhinga liqinisekile ukufaka umsebenzisi enkingeni ethile enkulu ngempilo yabo. Sebenzisa i-Orlistat kuphela ngokuhlangana nokubhekwa kwezokwelapha, ikakhulukazi uma usebenzisa ifomethi ye-120mg.

Ngabe u-Orlistat Usebenza Kanjani Njengomuthi We-Light Loss

A: Ungalahlekelwa Kanjani Isisindo ngokuthatha i-Orlistat?

Lapho wenza ukusetshenziswa kwe-Orlistat yokuncipha kwesisindo, umsebenzisi kufanele alandele izeluleko kudokotela wezokwelapha, ikakhulukazi lapho esebenzisa ifomu lomuthi i-120mg. Ngaphambi kokuthi lowo muntu aqale uhlelo lokunciphisa umzimba, kudingeka abe nokuqonda okuyikho ukuze enze ushintsho oluhle lomzimba.

Umuntu okhuluphele ngokweqile noma omkhulu ngokweqile udinga ukuqonda ukuthi umuthi awusiyo impendulo yezinkinga zawo. Isixazululo kuphela sokwehla kwesisindo esanele isikhathi eside ngokulungiswa kokudla, izindlela zokuphila, kanye nokungenisa uhlelo lokuzivocavoca oluqhubekayo.

Ngaphandle kwalokhu engqondweni, umuntu okhuluphele noma okhuluphele ekugcineni uzozama ukuncika ekusebenziseni kabi umuthi lapho engaboni imiphumela ayifunayo kwimizamo yawo. Ukusetshenziswa ngokweqile kwalesi sidakamizwa sokulahlekelwa isisindo kungabandakanya ukuthuthukiswa kwemiphumela emibi kakhulu engalimaza impilo yomsebenzisi.

Uma usebenzisa i-Orlistat nganoma iyiphi indlela, qiniseka ukuthi ulandela imiyalo yemithamo ebekwe esitsheni, noma usokhemisi ekhipha umuthi. Isilinganiso se-Orlistat kungahluka ngokuya nge-BMI yomuntu ngamunye. Noma kunjalo, ungasiphuthi umuthi isikhathi eside kunesinqunyelwe, noma esisohlwini lokufakwa kwephakethe lomkhiqizo.

Abantu abakhuluphele nabakhuluphele ngokweqile bangasebenzisa i-Orlistat eceleni kokudla okukhethekile, okunamafutha amancane, okunciphisa umzimba. Lapho kuhlelwa uhlelo lokudla lomuntu ngamunye, izazi zokudla kufanele ziqinisekise ukuthi amafutha awabizi ngaphezu kwamaphesenti angama-30 wamakhalori aphelele kunoma yikuphi ukudla.

Umuntu omningi kufanele alandele uhlelo lokudla nokuzivocavoca, aphuze i-Orlistat ngokuya ngemikhombandlela kadokotela wabo. Amaphrothokholi amaningi we-dosing akhipha imithamo emithathu yemithi kulo lonke usuku ehlukaniswe ngokulinganayo.

Uma umsebenzisi weqa ukudla, khona-ke kufanele weqe umthamo we-Orlistat odingekayo kuleso sidlo.

Uma weqa ukudla noma udla isidlo esingenawo amanoni, weqa umthamo wakho we-Orlistat walowodlo. Umsebenzisi kufanele aqale nokunaka amalebula wokudla kokudla. Funda ngohlu lwezithako nokunezakhi, futhi uvikele ukudla okunamafutha amaningi.

I-Orlistat nayo ingaphazamisa ukumuncwa okufanele kwamavithamini ancibilikiswa amanzi ekudleni kwakho. Ngakho-ke, iziguli kufanele zibuze udokotela wazo ukuthi zincome uhlobo lwevithamini abangalungenisa ngenkathi besebenzisa umuthi.

Abasebenzisi kufanele futhi bahlole umthamo wabo kanye nokusebenzisa umuthi. I-Orlistat isidakamizwa esinamandla okusebenzisa kabi i-off-script. Ngakho-ke, abanye abantu bangangenela umuthi wakho uma ungakunaki ukusetshenziswa kwakho.

Thatha noma yiziphi izithasiselo noma eminye imishanguzo okungenani amahora ama-2 ngaphambi komthamo wakho we-Orlistat. Leliqhinga lokudonsa livimbela noma yikuphi ukusabela okungekuhle nezinye izidakamizwa okungenzeka ukuthi uzisebenzisa. Uma ngabe unolunye uhlobo lwemithi, qiniseka ukuthi utshela udokotela wakho ngaphambi kokusebenzisa i-Orlistat.

B: Yini Okufanele Ngiyigweme Ngenkathi Ngisebenzisa I-Orlistat?

Lapho uthintana nodokotela wakho mayelana nempilo yakho nohlelo lwakho lokulwa nokukhuluphala, qiniseka ukuthi uxoxa nazo zonke ezinye izindaba zakho zezempilo nodokotela wakho. Udokotela udinga ukuthi aqaphele yonke imishanguzo oyithatha njengamanje ngaphambi kokuba anikeze i-Orlistat.

Eminye imithi ingadala ukuphikisana nezinye izidakamizwa, kuholele kumiphumela emibi kakhulu kumsebenzisi. Kufanele wazise udokotela wakho ngokusebenzisa kwakho noma imuphi umuthi olandelayo.

  • Imithi yesifo sikashukela somlomo noma ukusetshenziswa kwe-insulin
  • I-cyclosporine (iSandimmune, iNeoral, iGengraf)
  • I-Digoxin (Lanoxin, digitalis, Lanoxicaps)
  • I-Levothyroxine (Levoxyl, Synthroid, Levothroid)
  • Imithi yokunciphisa igazi njenge-warfarin (Coumadin)

Kubalulekile ukuqaphela ukuthi lolu akulona uhlu olubanzi lwezidakamizwa olungadala izinkinga ngokusetshenziswa kwe-Orlistat.

Yenza isikhathi sokubonisana nodokotela wakho ukuthi nixoxe ngayo yonke imishanguzo kadokotela, izithasiselo, neminye imikhiqizo ye-OTC oyisebenzisayo engase ibangele ukusebenzisana lapho usebenzisa i-Orlistat.

Akumelwe ngaphansi kwanoma yiziphi izimo thatha i-Orlistat ngaphandle kokuthinta uchwepheshe wezokwelapha kuqala. Ngenkathi uhlobo lwe-60mg lutholakala kalula ukusetshenziswa kwe-OTC, umsebenzisi kufanele aqhubeke abonane nodokotela wezokwelapha ngaphambi kokuwengeza ohlelweni lwabo lokudla nokuzivocavoca.

Uma uthathwa ngemithamo ephezulu noma isikhathi eside, i-Orlistat ingadala izinkinga zempilo ezinzima. Labo bantu abacabanga ukuthi kungenzeka ukuthi banqwabelanise ngokweqile e-Orlistat kufanele bashayele i-hotline usizo hotline ngokushesha futhi bacele i-ambulensi.

Iziguli kufanele zigweme ukuphuza i-Orlistat uma zinokungezwani nezinye zezithako ekwelashweni. Ungathathi i-Orlistat uma ubhekene nanoma yiziphi zalezi zimo zempilo ezilandelayo.

  • Isifo se-malabsorption esingamahlalakhona
  • Izinkinga ze-Gallbladder
  • I-thyroid engasebenzi
  • Umlando weGallstone
  • Umlando we-pancreatitis
  • Isifo sesibindi
  • Isifo sikashukela thayipha mina noma II
  • Izinkinga zokudla ezifana ne-anorexia noma i-bulimia
  • Uma njengamanje usebenzisa omunye umuthi wokulahlekelwa isisindo noma imikhiqizo ye-OTC

4. Yimiphi Imiphumela Ongayilindela Ngokusebenzisa i-Orlistat?

Kubalulekile ukuthi umuntu ngamunye aqonde ukuthi ayikho into efana nomuthi “wokunciphisa isisindo somzimba.” Ngenkathi ukusetshenziswa kwe-Orlistat eceleni kohlelo lokudla olukhawulelwe kilojoule kuzosheshisa ukulahleka kwesisindo kubantu abakhuluphele noma abakhuluphele ngokweqile, kudingeka babeke okulindelwe okunokwenzeka ngenqubo.

Imiphumela ye-Orlistat ziyehluka kuye ngomuntu, futhi mhlawumbe ngenxa yokuthi wonke umuntu une-metabolism eyingqayizivele nohlobo lomzimba. Kodwa-ke, ungalindela ukuthi isilinganiso sokulahlekelwa kwamafutha sibe sesilinganisweni, futhi ukusebenzisa lo muthi kungakusiza ukuthi uchithe amaphawundi ambalwa ngeviki kunokudla namasu okuzivocavoca uwedwa.

Kodwa-ke, ukulindela ukulahleka ngokushesha kwamafutha akunangqondo. Amathuba ukuthi kwathatha isiguli iminyaka ethile, mhlawumbe ngisho namashumi eminyaka, ukufinyelela isimo saso sokukhuluphala ngokweqile. Ngakho-ke, ukulindela ukuthi amanoni ancibilike ubusuku bonke, noma ngisho ezinyangeni ezimbalwa, kuzoshiya umsebenzisi ezizwa edangele futhi edumele ngemiphumela yabo.

Odokotela bachaza ukunciphisa umzimba ngokwezinga lesisindo njengokuncipha kwesisindo somzimba somuntu, sika-5% noma ngaphezulu konyaka. Ucwaningo lukhombisa ukuthi ngaphezulu kwe-40% ye Abasebenzisi be-Orlistat bafeze lo mgomo, uma nje belandela izeluleko zobungcweti zikadokotela nodokotela wezempilo.

Lolu cwaningo lukhombisa nokuthi labo bantu ababedla ukudla okunomkhawulo wekhalori, kanye nokuthola ukuzivocavoca njalo, kanye nokusebenzisa i-Orlistat, balahlekelwe ngama-lb ama-5.7-lbs angaphezu kweqembu lokulawula ababengasebenzisi i-Orlistat. (5,6)

(1) Yini Izinzuzo Zokusebenzisa i-Orlistat?

Kunenzuzo enkulu yokusebenzisa i-Orlistat njengengxenye yohlelo lokulahleka kwesisindo oluhlelwe kahle futhi lubhekwe kahle. Umuthi uyasebenza ekuvimbeleni umzimba ekufuneni amafutha, ngaleyo ndlela kunciphise ngokumangazayo ingxenye enkulu yamakhalori aphelele afakwe yisiguli.

Kodwa-ke, ngenkathi i-Orlistat ingukungezwa okuwusizo ekudleni okulahlekelwe isisindo, futhi iveza imiphumela ebonakalayo, asikwazi ukubeka phansi ukuthi abantu akufanele basebenzise lesi sidakamizwa njenge-crutch. Labo bantu abathembele kokubhalwe phansi noma ekunikezelweni njengetshe lesisekelo sohlelo lwabo lokwehliswa kwesisindo bazothola imiphumela yokuntuleka.

Abanye abantu abenzi zinguquko kuzindlela zabo zokudla noma zokuvivinya umzimba futhi, esikhundleni salokho, bathembela ku-Orlistat ukwenza umsebenzi. Kodwa-ke, laba bantu bazithola bedumele ngemiphumela yabo yokulahlekelwa isisindo.

Izinzuzo ze-Orlistat uhlelo lokunciphisa umzimba olunesakhiwo esichaziwe nezinhloso ezicacile. Akunakulindeleka ukuthi isiguli sibe nolwazi noma isisusa sokuqedela ukuguqulwa komzimba wodwa.

Ngakho-ke, ukuqasha umuntu okondlayo kanye nomqeqeshi, nokulandela uhlelo lokudla nokuzivocavoca umzimba kumele kube kunoma ngubani owenza uhlelo lokunciphisa umzimba.

Iningi labantu abakhuluphele nabakhuluphele ngokweqile bathola ukuthi bathola ukwehla kwesisindo okukhulu emasontweni amabili okuqala kokudla ukudla okunempilo nokuzivocavoca - futhi lokho kungaphambi kokuba baveze noma yiziphi izithasiselo noma izidakamizwa ezifana ne-Orlistat.

Kodwa-ke, abanye abantu bangadonsa kanzima ukuze banciphise isisindo noma ngabe balandela uhlelo olufanele lokudla nokuvivinya umzimba. Abanye bangathola ukuthi inqubekelaphambili yabo yenqubekela phambili isebenzisa izindlela zemvelo. Lababantu bangathola ukuthi i-Orlistat ibazuzisa kulesi simo, ibavumele ukuba balahlekelwe isisindo ngendlela eqhubekayo kukho konke ukuguqulwa komzimba wabo.

(2) Yiziphi Izingozi Zokusebenzisa i-Orlistat?

Abantu ababheka ukusebenzisa i-Orlistat kufanele bathathe isikhathi ukubukeza uhlu lwemiphumela emibi ye-Orlistat ehambisana nokusetshenziswa komuthi wokulahlekelwa isisindo. I-Orlistat ingumuthi onamandla owenzelwe ukusetshenziswa eceleni kokudla okukhawulelwe kokhalori okuhlelelwe umuntu onothe ngokweqile ngudokotela ofanelekayo onempilo.

Uhlobo lomuthi lwe-OTC lungatholakala kalula ukuthi luthengwe ngaphandle kokuthola umuthi, kepha akekho umuntu okufanele asebenzise i-Orlistat ngaphandle kokukhuluma nodokotela wabo kusengaphambili.

Ezivivinyweni zemitholampilo ezibandakanya ukuphathwa kwe-Xenical kwiziguli, ama-27% athola amabala ezinamafutha ezingutsheni zawo zangaphansi, ama-24% wabasebenzisi abathola igesi elandelwa ukuphuma kokuzenzela kokuzenzela, ama-22% wabasebenzisi bathola ukuqala kokuphuthumayo ngokuzimela, u-11% ukhombise ukwanda kokufika kwabo inani lokuhamba kwamathumbu, kanye nama-8% wokuqothuka okungapheli.

Kwabasebenzisi abaningi, isifo sohudo futhi siwumphumela ojwayelekile wokusebenzisa umuthi, ikakhulukazi lapho uqala ukusebenzisa umuthi we-weightloss.

Imiphumela yokungezwani komuthi ayivelakancane, futhi eminye yemiphumela ejwayelekile abasebenzisi abayibona emasontweni ambalwa okusebenzisa i-Orlistat ifaka okulandelayo.

  • Amabala noma amanoni ku-underwear yakho
  • Izihlalo ezinamafutha noma ezinamafutha
  • Amafutha ansundu noma anombala osawolintshi osesihlalweni
  • Ugesi ohambisana nokukhipha amafutha
  • Isihlalo esikhululekile, ukwanda kokuphuthuma kokungajwayelekile, kanye nokwehluleka komsebenzisi ukulawula ukunyakaza kwamathumbu abo
  • Ukwanda kokuvama kokunyakaza kwamathumbu
  • Isicanucanu, ukugabha, Ubuhlungu besisu, isisu, nobuhlungu bobucayi
  • Ukukhathala nobuthakathaka, izihlalo ezinombala obumba, umchamo omnyama, ukulahleka kwesifiso, ukulunywa, noma ukubukeka kwe-jaundice (kuphuzi kwabamhlophe bamehlo noma kwesikhumba)

Ezinye izingqinamba ezingavamile iziguli ezihlangabezana nazo lapho zithatha i-Orlistat zifaka okulandelayo.

  • Izinkinga nezinsini namazinyo
  • Ukuthuthukiswa kwezimpawu ezifana nokubanda
  • Ukuthuthukiswa kwezimpawu ezinjengomkhuhlane
  • Ubuhlungu bekhanda nobuhlungu emuva
  • Thambisa emisebeni yesikhumba eyedlulele

Abasebenzisi kufanele bazi ukuthi lolu akulona uhlu oluphelele lwemiphumela emibi engaqhamuka lapho kusetshenziswa i-Orlistat. Uma uhlangabezana nemiphumela emibi noma impendulo engemihle kulo muthi, bika okuhlangenwe nakho kwakho ku-FDA ku-1-800-FDA-1088.

5. Yini Abasebenzisi Abayishoyo nge-Orlistat?

Ukubheka izibuyekezo ze-intanethi ngabasebenzisi, kuholela emiphumeleni ehlukahlukene, kokubili futhi yokulwa nokusetshenziswa kwomuthi. Ukubuyekezwa kwe-Orlistat kususela kubantu abathole imiphumela evelele kulabo abathola imiphumela emibi kakhulu.

Kodwa-ke, kubukeka sengathi iningi lamacala ahilela abantu ababemakhulu, noma ama-BMI angaphezu kwama-27, banokuhlangenwe nakho okuhle ngomuthi. Konke ukubuyekezwa okuhle esikutholile ngomuthi wokunciphisa umzimba kusuka kubasebenzisi abanolwazi ababephethwe ukuguqulwa komzimba ezandleni zikachwepheshe wezokwelapha.

Ngakho-ke, laba bantu bahlele isu labo lokunciphisa isisindo ngendlela efanele. Bonke baqasha isazi sezempilo, bathola udokotela njalo ngekota, futhi banamathela esimisweni sokudonswa kwemithi eselulekwa uchwepheshe wabo wezokwelapha.

Nasi isibonelo semiphumela yangempela ye-Orlistat esiyithole online.

"Igama lami nginguRon, futhi nganginamafutha ngokweqile lapho kwakucekela phansi impilo yami. Ngokuhamba ngiphuma ngewindi, nempilo yami isiwohloka, ngaphendukela kudokotela wami ukuze angisize. Le dokhumenti yangifaka ukuxhumana nodokotela wezokudla, futhi ngaqonda izidingo zami zekhalori zosuku.

Ngemuva kokudla izinyanga eziyisithupha nokugijima nsuku zonke, ngabona imiphumela emihle, kepha intuthuko yami yaqala ukuqina. Udokotela wami uphakamise ukuthi ngizame i-Xenical (Orlistat). Angicabanganga kangako ngakho, kodwa ukuncipha kwami ​​kuqhubeke ngemuva kosuku lwesibili ngisebenzisa umuthi.

Ngemuva konyaka, futhi ngizizwa njengomuntu omusha. Sengiphakathi kwesisindo segoli lami, futhi amakhilogremu aqhubeka eza. "

-

IRon Swanson, Jacksonville, FL, USA.

Kubalulekile ukuqaphela ukuthi akuwona wonke umuntu ozozwa lo mphumela, kepha lokhu kuyimpawu enhle yemiphumela ongayilindela lapho konke kuhamba kahle.

Kulesi sibonelo, imiphumela kaRon yaba ngumphumela omuhle, kodwa lokho akusho ukuthi omunye umuntu akakwazi ukuziphindisela eyakhe imiphumela, inqobo nje uma benokuqashwa okufanele kwezokwelapha.

6. Izindlela ezibalulekile zokusebenzisa i-Orlistat njenge-Weight Loss Drug

Ukukhuluphala ngokweqile kusongela impilo yabantu baseMelika ezweni lonke. Izinga lokukhuluphala liyenyuka kubo bobabili abantu abadala, intsha, kanye nezingane, kanye neNingizimu ne-Eastern States yase-US okunzima ukuhlaselwa yilolu bhubhane olukhulayo.

Ukukhuluphala kuholela ekuthuthukisweni kwezinkinga eziningi zezempilo ezingamahlalakhona, njengesifo sikashukela, umfutho wegazi ophakeme nesifo senhliziyo. Lesi simo sibanga nokufa kwe-18% yabo bonke abantu baseMelika abaneminyaka engama-40 kuye kwengu-85 ubudala.

Abantu abaningi baseMelika baphendukela ezidakamizweni nakwizithasiselo zokubasiza ukusheshisa izinhlelo zabo zokunciphisa umzimba. Kodwa-ke, iningi lalaba bantu futhi alwenzi ngokwanele ukushintsha indlela yabo yokuphila, ukudla, nokuzivocavoca ngaphambi kokusebenzisa ezinye izindlela zokunciphisa umzimba.

Abantu baseMelika badinga ukuqonda ukuthi akukho ndlela emfishane yokulahlekelwa amafutha omzimba. Ukuthola ulwazi lokudla okufanele nokuvivinya umzimba kubalulekile ekubuyiseleni isisindo somzimba wakho. Ngaphambi kokuguqukela ekusebenziseni izidakamizwa ezingaba yingozi ngokweqile, kungcono ukuthi uqinisekise ukudla okudla nokuzivocavoca kahle kuqala.

Cabanga kuphela ukusebenzisa i-Orlistat ngemuva kokubonisana nodokotela wakho ngemigomo yakho yokunciphisa isisindo. Udokotela wakho uzokuthumela kumondli ofanelekayo ngohlelo lokudla oluhlangabezana nezidingo zakho ze-caloric zokulahleka kwamafutha.

Labo bantu abazama uhlelo lokunciphisa umzimba kufanele baqinisekise ukuthi bakha iqembu elizungeze uma bafuna ukubona imiphumela. Udokotela wakho, umondli wezempilo, i-physiotherapist, kanye nomqeqeshi wakho siqu bakha ithimba lakho lokusekelwa ukuze likunikeze ithuba elihle lokunqoba noma yiziphi izithiyo endleleni yakho zokufeza izinhloso zakho zokunciphisa umzimba.

I-Orlistat ifana nokungeza i-jet fuel enjini esebenza kahle eyenziwe kahle. Lapho iziguli zinendlela yazo yokudla neyokuzivocavoca ngaphansi kolawulo, ukwengeza umuthi wokunciphisa umzimba njenge-Orlistat kungasheshisa kakhulu imiphumela.

Ngaphambi kokuthi bathathe isinqumo sokuthatha i-Orlistat, iziguli kumele zixhumane nodokotela wezempilo ukuze zibone ukuthi ziyahlangabezana yini nemigomo efanelekile yokwelashwa.

Uma ubuyekeza imiphumela yokuhlangenwe nakho komsebenzisi ne-Orlistat, kuyisikhwama esixubile semiphumela. Kodwa-ke, kubonakala sengathi labo bantu abathatha i-Orlistat ngokuyalelwa wudokotela futhi baqashe iqembu elifanele lokusekelwa bayafinyelela imiphumela abayifisayo.

Ohlangothini lwe-flip, kunenqwaba yabantu abanokuhlangenwe nakho okubi ngokusebenzisa i-Orlistat. Kungenxa yalesi sizathu ukuthi kubaluleke kakhulu ukuthi abantu ngamunye bathathe i-Orlistat ngaphansi kokunakekelwa uchwepheshe wezokwelapha.

I-Orlistat inikela ngabantu abakhuluphele nabakhulu ngokweqile nge-FDA evunyelwe ngaphezulu kwenketho ye-counter yokuthuthukisa imizamo yabo yokulahlekelwa isisindo.

Kubalulekile futhi ukuqaphela ukuthi zonke iziguli ezisebenzisa lo muthi, zidinga imfundo ephathelene nokuqhubeka kokuguqulwa kokuziphatha ngesikhathi sokusebenzisa umuthi.

Okubhekwayo

  • U-Anderson JW, Schwartz SM, Hauptman J, et al. Imiphumela emincane yedosi ye-orlistat kwesisindo somzimba ngobumnene kubantu abanozalo ngokweqile: isonto eli-16, isivivinyo esilawulwa ngamehlo, esinezimpawu eziphindwe kabili. Ann Pharmacother. 2006; 40 (10): 1717-1723
  • Smith SR, Stenlof KS, Greenway FL, et al. I-Orlistat 60 mg inciphisa izicubu ze-visceral adipose: isivivinyo esinama-24-veki engahleliwe, esilawulwa nge-placebo. Ukukhuluphala (i-Silver Spring). 2011; 19 (9): 1796-1803.
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