Imizuzu engama-30 Ukwazi i-Nootropic Pramiracetam-AASraw
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I-Nootropic Pramiracetam

Yini i-Nootropic?

Leli gama lisho amakhemikhali emvelo noma okwenziwa angaba nomthelela kumakhono engqondo. Zingaba ukudla Izithako, izinto zokwenziwa, noma imishanguzo kadokotela. Izibonelo zemithi kadokotela ye-nootropic yiRitalin, isikhuthazi esisetshenziselwa ukwelapha i-ADHD noma iMemantine, umuthi wokwelashwa komqondo.

Izithuthukisi eziqondayo ukukhulisa ubuhlakani, ubuhlakani, kanye nogqozi kuyinzuzo enkulu esimweni sanamuhla sokuncintisana. Ungase uzizwe zibizwa ngokuthi "izidakamizwa ezihlakaniphile" kodwa zingaphezulu kakhulu kwalokho.

Igama elithi nootropic livela ezimpandeni zesiGreki: "nous", okusho ukuthi ingqondo, ne "tropin", okusho ukujika noma ukugoba (njengomfula).

 

Izici ezijwayelekile zeNootropics

Ukuze ikhompiyutha yamakhemikhali ibhekwe njenge-nootropic, idinga ukuhlangabezana nenqubo ethile. Ngokuvamile, i-nootropic eyamukelekayo

  • Ithuthukisa inkumbulo
  • Kuthuthukisa ukusabela ngaphansi kwengcindezi
  • Kuvikela ubuchopho ekulimaleni ngokomzimba noma ngamakhemikhali
  • Ithuthukisa ukulawula kwe-cortical / subcortical
  • Inobuthi obuphansi noma imiphumela emibi

Izinhlanganisela zokwenziwa ezilandela lezi zindlela zisungulwe muva nje, kepha amasiko asendulo ezokwelapha eChina naseNdiya akhombisa ukusetshenziswa kwensangu, i-ginkgo biloba, namanye amakhambi ngalezi zizathu nje.

Kungani iPramiracetam idume?

I-Pramiracetam iyingxenye yomndeni we-racetam, iqembu lamakhemikhali okwenziwa abelana nge-pyrrolidone nucleus. Izidakamizwa kulo mndeni zingama-anticonvulsants, inkumbulo, nezithuthukisi zokuhlushwa.

I-Pramiracetam ithinta kahle ukutholwa kwezinkumbulo. Ucwaningo lukhombisa ukuthi i-neuroprotective. Ngokungafani nemithi eminingi emndenini we-racetam, ukusebenza kwayo kwahlolwa kubantu abadala abaphilile. Iningi lamakhemikhali e-racetam ahlolwe kwabadala asebevele bencipha.

I-nootropic enamandla enemiphumela ehlala isikhathi eside eyakha ngokuhamba kwesikhathi. Obunye ubufakazi bukhombisa ukuthi kungasiza ngokulimala kwengqondo okulimazayo.

I-AASraw ingumkhiqizi oqeqeshiwe weNootropic Pramiracetam.

Sicela uchofoze lapha ukuthola ulwazi lwesilinganiso: Oxhumana nathi

 

I-Pramiracetam Incazelo

I-Pramiracetam (N- [2- [di (propan-2-yl) amino] ethyl] -2- (2-oxopyrrolidin-1-yl) acetamide, CI-879, Pramistar, Neupramir, Remen) iyi-nootropic encibilika ngamafutha esigabeni se-racetam samakhemikhali.

I-Pramiracetam (i-CAS: 68497-62-1) kukhombisile ukuthi kuyasebenza ekwelapheni ukuphazamiseka kokuqonda kwemvelaphi ye-cerebrovascular and traumatic. Ukuhlolwa kwabantu abanenkumbulo engasebenzi kahle kukhombisile ukuthi iPramiracetam iyakwazi ukuthuthukisa inkumbulo. Yize lungekho ucwaningo olukhombisa ukuthi lokhu kuyenzeka kubantu abasha abanempilo, abaningi babike ngokuzwa imiphumela yokuthuthuka kwenkumbulo nokukhumbula. Incazelo yokuthi kungani iPramiracetam ithuthukisa inkumbulo, ukuthi ikhombisile ukukhuphula ukutholwa okuphezulu kwe-choline.

Ngokwesayensi, uCholine i-molecule eyandulelayo ye-neurotransmitter acetylcholine, efana kakhulu nevithamini futhi iyisakhi esibalulekile. I-Choline itholakala kwezinye izitshalo nezitho zezilwane noma ubisi. Ukuba nokudla okunomsoco futhi ngaleyo ndlela kube nokutholakala okwanele kwe-choline kanye nokwengeza izinhlanga ezifana nePramiracetam ezandisa ukutholwa kwe-choline, kungaba nomthelela omuhle enkumbulweni.

I-Pramiracetam iyi-molecule ye-racetam ehlanganisiwe enokufana kokwakheka ne-molecule yomzali iPiracetam. Yaqala ukwenziwa ngo-1984 ngamandla ayo okuvikela i-amnesia evela kugesi. Uma kuqhathaniswa namanye amalungu omndeni we-racetam, iPramiracetam ayicwaningeki kangako kepha inobufakazi bokusizakala kwayo kubantu.

Ezifundweni, i-Pramiracetam ibonakale isebenza kahle lapho ithathwa ngaphambi nje kokuhlolwa okungenza kube lula ukulekelelwa ngesikhathi sokuhlolwa kwezemfundo noma izigaba zomsebenzi ezijulile lapho inkumbulo ethuthukisiwe nemisebenzi yokuqonda isebenza kahle. Izifundo zabantu zisekela lo mcabango kepha azihlinzeki ngobufakazi obenele bezibalo kuze kube namuhla.

 

I-Pramiracetam Indlela Yokusebenza

Njengawo wonke ama-racetam, izindlela ezenziwa ngemuva kwe-pramiracetam aziqondakali ngokuphelele, ikakhulu ngenxa yokushoda kocwaningo olunzulu.

Kodwa-ke, ezinye izifundo zakuqala zikhombe izindlela ezimbalwa ezilandelayo:

May Ingakhuphula amazinga e-acetylcholine (ngokwandisa ukufakwa kwe-choline kumaseli ngama-30-37%);

▪ Ingakhuphula ukukhiqizwa kwe-nitric oxide ebuchosheni;

May Kungabandakanya ama-hormone adrenal njenge-aldosterone ne-cortisol (corticosterone);

Kodwa-ke, idatha emayelana nezinqubo ezingenhla iza cishe kuphela ezifundweni zezilwane - ikakhulukazi kumagundane namagundane - ngakho-ke azikho iziphetho ezinamandla ezingenziwa okwamanje mayelana nezinqubo ezingaba khona ze-pramiracetam ebuchosheni babasebenzisi babantu abaphilile.

I-Nootropic Pramiracetam

I-Pramiracetam Izinzuzo

I-Pramiracetam iyi- i-nootropic yangempela, idalwe ngokukhethekile ukuthuthukisa ukuqonda. Izinzuzo nemiphumela yayo kufaka okulandelayo:

 

  • Imemori Ethuthukisiwe

I-Pramiracetam iyisithuthukisi sememori esiqinisekisiwe, ihlolwe kabanzi emashumini ambalwa eminyaka futhi ikhonjiswe ngempumelelo kuzo zombili izifundo zezilwane‍ kanye nokuhlolwa kwemitholampilo yabantu abadala abanokukhubazeka kwengqondo ngenxa yokulimala kobuchopho.

I-Pramiracetam ithuthukisa inkumbulo zombili ngokuvuselela i-hippocampus, ingxenye yobuchopho ngokuyinhloko enesibopho sokwakha izinkumbulo ezintsha nangokusebenza njenge-anti amnesic enamandla enciphisa ukukhohlwa. Abasebenzisi abaningi futhi babika intuthuko enkulu kusivinini sokukhumbula, isimangalo esiqinisekiswe yizifundo zezilwane

 

  • Ukuqapha okukhudlwana nokwandiswa kwamandla okufunda

Isithunzi sikaPramiracetam njengesithuthukisi esijwayelekile sokuqonda esiqinisa ukuqwashisa futhi sandise amandla okufunda sikwenze kwaba yinto ekhethwayo phakathi kwabafundi abafuna insiza yokufunda ethembekile.

Yize kungekho zifundo zabantu ngale miphumela ethile ebhaliwe, ucwaningo lwezilwane lukhombisa ukuthi i-pramiracetam inikela kuzindlela ezisebenza ekufundeni nasekuthuthukisweni kwememori ngokwandisa umsebenzi we-neuronal uhlobo lwe-nitric oxide synthase (NOS) ku-hippocampus. i-plasticity, yomibili ebaluleke kuzo zonke izici zokuqonda.

I-Pramiracetam yaziwa nangokuthi yandisa ukutholwa okuphezulu kwe-choline ku-hippocampus, ngaleyo ndlela ngokungaqondile ikhiqize ukukhiqizwa kwe-acetylcholine, i-neurotransmitter ebalulekile ehlotshaniswa kakhulu nokufunda nokwazi.

 

  • Ukwelashwa kwe-Dementia

Ukuhlolwa kwelebuli evulekile ezigulini ezinokuwohloka komqondo okuyisisekelo okukhubazayo kubonisa ukuthi iPramiracetam iguqule ngempumelelo i-amnesia, ithuthukisa kakhulu ukukhumbula nokunciphisa ukukhohlwa.

Kwezinye izifundo, ezilinganise imiphumela ye-pramiracetam namanye ama-nootropics ekilasi le-racetam ezigulini ezinokuwohloka komqondo okuphakathi kuya kokulingene, kube nokuthuthuka okulinganisekayo kokuqonda nokukhumbula. Le miphumela kungenzeka ichazwe, okungenani ngokwengxenye, ekuthuthukiseni i-nootropic yama-neurotransmitter akhona.

Yize i-pramiracetam ingavunyelwanga njengokwelashwa kwe-Alzheimer e-US, ijwayele ukunikezwa eYurophu ukwelashwa komqondo kanye nezinye izingqinamba ezihlobene nesifo i-Alzheimer's kanye nezinye izifo zemizwa.

  • Ukuziqhenya komphakathi

Ngenkathi kungekho lucwaningo olubhaliwe ngomphumela we-pramiracetam ekusetshenzisweni komphakathi, abasebenzisi abaningi babika ukuthi kubenza babe nobuciko bokuxoxa futhi bakwazi ukukhuluma kahle emphakathini. Lo mphumela ungachazwa, okungenani ngokwengxenye, ngomphumela we-pramiracetam owehlulekayo ngokomzwelo, sometimesokuthi kwesinye isikhathi kuchazwe kufane nokaRitalin. Lo mphumela unganciphisa ukukhathazeka komphakathi futhi, futhi, uthuthukise ukushelela komphakathi.

 

  • Amandla we-Neuroprotective

I-Pramiracetam yaziwa ngokuba nemiphumela eminingi ye-neuroprotectant, ekwazi ukuthuthukisa ukuqonda kubantu abaye babhekana nokuhlukumezeka kobuchopho.

Ucwaningo luye lwabonisa ukuthi lunomphumela we-neuroprotective obonakalayo lapho usetshenziswa ngesikhathi sokuhlinzwa kwe-coronary bypass kanye nasekwelapheni ukuphazamiseka kwengqondo kwengqondo yemvelaphi ye-cerebrovascular.

I-AASraw ingumkhiqizi oqeqeshiwe weNootropic Pramiracetam.

Sicela uchofoze lapha ukuthola ulwazi lwesilinganiso: Oxhumana nathi

 

I-Pramiracetam Isikali sereferensi

I-Pramiracetam ngokujwayelekile iza ngesimo se-powder, amaphilisi asele enziwe, noma amaphilisi. Abanye abasebenzisi babika ukuthi ifomu le-powder linokunambitheka okuqinile okungathandeki, ngakho-ke bakhetha ukusebenzisa amafomu we-capsule noma we-tablet esikhundleni salokho.

Ngokusho kwabanye abacwaningi, amafomu we-powder ne-capsule angaba nesilinganiso sokumunca ngokushesha kunefomu lethebulethi. Kodwa-ke, amandla nokusebenza okuphelele kukholakala ukuthi acishe alingane ngezinhlobo ezahlukahlukene.

Kokunye kokuhlolwa okumbalwa okwenziwe kuze kube manje, umthamo ophelele we-1,200 mg usetshenzisiwe, uhlukaniswe waba ngamanani amabili we-600-mg noma imithamo emithathu ye-400-mg esakazeka usuku lonke.

Njengelungu lomndeni we-racetam wezidakamizwa, i-pramiracetam kukholelwa ukuthi incike ku-choline ngemiphumela yayo, futhi ukuyisebenzisa, ngakho-ke, kungaqeda ukunikezwa kwe-choline yomzimba. Ngalesi sizathu, kwesinye isikhathi kunconywa ukuhlanganisa ama-racetams nomthombo we-choline, njenge-alpha-GPC noma i-citicoline. Kodwa-ke, lesi siphakamiso sisekelwe kuphela kudatha evela ocwaningweni olulodwa lwesilwane, ngakho-ke lokhu akufanele kutolikwe njenganoma yiluphi uhlobo lwezincomo "ezisemthethweni" noma "ezigunyazwe ngokwelashwa".

 

Imininingwane ebalulekile: I-Pramiracetam Stack

I-Pramiracetam isebenza kahle iyodwa kepha futhi ingaba amandla amakhulu amanye ama-nootropics, ikhulise ukusebenza kwayo.Yiyona potentiator ephumelela kakhulu kwamanye ama-racetam, okwenza kube ukwengeza kwemvelo kwabaningi i-nootropic izitaki.

Ukungeza i-choline ukwengeza isitaki se-pramiracetam singaba nezinzuzo eziningi. Ayigcini nje ngokukhulisa imiphumela ye-pramiracetam, kepha ingavimbela nokuphathwa yikhanda, okuyimiphumela emibi kakhulu ebikiwe. .

Ngezibonelo ezi-2 mayelana I-Pramiracetam i-stack:

 I-Pramiracetam ne-Oxiracetam Stack

I-stacking pramiracetam ene-energy enhancer efana ne-adrafinil noma i-oxiracetam ingaqinisa ukuqwashisa ngokwengqondo futhi iyelule isikhathi eside.

❷Pramiracetam kanye ne-Aniracetam Stack

Ukubeka i-pramiracetam nge-agent enamandla yokulwa nokukhathazeka njenge-aniracetam kunganikeza abasebenzisi ukugxila okuphezulu nokugxila ngenkathi kuthuthukisa imizwa futhi kunciphise imizwa yokukhathazeka kwengqondo nokukhathazeka. Abanye abasebenzisi bathi lesi sitaki sikhuthaza ukushelela komphakathi futhi sithuthukise ikhono labo lokusebenza komphakathi.

 

Imiphumela ye-Pramiracetam Side

I-Pramiracetam ivame ukubekezelelwa kahle ngisho nakwimithamo ephezulu, futhi kunemiphumela engemihle emibi kakhulu ebhaliwe.

Kunemibiko engajwayelekile yemiphumela emibi emincane neyesikhashana, kufaka phakathi ikhanda, ukucindezeleka kwamathumbu, nemizwa yokwethuka noma yokuphazamiseka.‍ Ezimweni eziningi, imiphumela emibi ihlotshaniswa nomthamo omkhulu futhi ingagwenywa ngokunciphisa amanani angenisiwe.

Ubuhlungu bekhanda obuhambisana nokuncipha kwe-choline kungumphumela ojwayelekile we-racetam uhlobo lwe-nootropics futhi ungavinjelwa ngokuthatha i-pramiracetam ngokuhlangana ne-supplementary choline.

I-Pramiracetam ayiyona umlutha, futhi akukho miphumela emibi kakhulu yokusetshenziswa kwesikhathi eside ebhaliwe. Kunobufakazi bokuthi i-pramiracetam ingahle ikhuthaze impilo yobuchopho futhi ibuyise nokusebenza ebuchosheni bokuguga.

 

Iphi Indawo Engcono Kakhulu Yokuthenga I-Pramiracetam Online? 

Yize kuyiqiniso ukuthi iPiracetam ingenye yama-nootropics athembisa kakhulu, inezifundo ezimbalwa kuphela zezokwelapha futhi iningi lazo, uma lingelona elomhla, liyizifundo zocwaningo olusekelwe ezilwaneni. Izinzuzo ziyamangalisa.Kuzuzisa kakhulu kubantu abadala asebekhubazekile ngokwengqondo kepha futhi kunconywa ukuthi kuthathwe yizingane nabantu abadala abancane ngokuya ngezidingo zabo.Kuphephile ukusetshenziswa ngenkathi kusebenza kakhulu kuphela uma kubekiwe nokunye ama-nootropics.

Kunezindawo eziningi ezinePiracetam ezithengiswayo online. Kodwa-ke, kungcono ukuthenga kuwebhusayithi ehlangabezana namazinga ekhwalithi kulo mkhakha. I-AASraw umphakeli onokwethenjelwa wama-nootropics, yonke imikhiqizo yawo ikhiqizwa ngaphansi kwe-cGMP futhi ikhwalithi ingalandelelwa nganoma yisiphi isikhathi, ngokwazi kwethu. Ungacabanga ngazo uma ufuna ukuthenga iPramiracetam powder.

Kungathengwa kangcono kulo mthengisi. Bathengisa izinhlanganisela ezethembekile nge-CoA futhi bathumele emhlabeni wonke. Njenganoma iziphi ezinye izidakamizwa, ezinye izitolo zingadinga iphepha ngaphambi kokuthenga. Amanani ePiracetam nawo angahluka ngokuya ngendawo.

I-AASraw ingumkhiqizi oqeqeshiwe weNootropic Pramiracetam.

Sicela uchofoze lapha ukuthola ulwazi lwesilinganiso: Oxhumana nathi

 

Izikhombo

[1] Abasebenzi, Ishidi Eliphinki. Meyi 27, 1991 I-Cambridge Neuroscience Ithuthukisa iPramiracetam kaWarner-Lambert

[2] Ukuqokwa kwesizinda sedatha yezintandane nokugunyazwa kwe-FDA kufinyelelwe ngo-Agasti 2, 2015

[3] Drugs.com Drugs.com Ukufakwa ohlwini kwamazwe omhlaba kwepramiracetam Page kufinyelelwe ngo-Agasti 2, 2015

[4] U-Auteri et. al. Iphephabhuku lamazwe omhlaba locwaningo lwemitholampilo, 12 (3), 129-132 (1992-1-1)

[5] Isipiliyoni ekusetshenzisweni kwe-pramistar, ukulungiswa okusha kwe-nootropic, ekwelapheni ukuphazamiseka kwememori ezigulini ezine-cerebrovascular pathology. 2003 Dec.

[6] Ukusetshenziswa kwama-nootropic agents ekwelapheni okuyinkimbinkimbi kweziguli ezinokuqubuka kobuchopho. 2008 uMeyi 30.

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