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I-Ethynyl estradiol (57-63-6)

Isilinganiselwa:
5.00 koku 5 ngokusekelwe ku 1 isilinganiso ikhasimende
SKU: 57-63-6. Isigaba:

I-AASraw ine-synthesis nekhono lokukhiqiza kusuka kugramu iye ku-oda le-Ethynyl estradiol (57-63-6), ngaphansi komthethonqubo weCGMP nohlelo lokulawula ikhwalithi olandelwayo.

Product Incazelo

Ividiyo ka-Ethynyl estradiol (57-63-6)


I-Ethynyl estradiol (57-63-6) Sukukhishwa:

Isakhiwo samakhemikhali: Igama Product: Ethynyl estradiol
Thenga i-Ethynyl estradiol (57-63-6) hplc≥98% | I-AASraw Cas Cha: 57-63-6
Formula Yamamolekhula: C20H24O2
isisindo Yamamolekhula: 296.4
Standard: I-CP, i-EP, i-USP, i-IP
Isitoreji: Omile, kumnyama futhi ku-0 - 4 C okwesikhashana (izinsuku kuze kube ngamasonto)
Imibhalo (COA & HPLC njll): Iyatholakala

I-Ethynyl estradiol (57-63-6) Dukubhalwa:

I-Ethinyl Estradiol powder iyi-estrogen enobuthi. Indlela yokusebenza yesenzo se-ethinyl estradiol injenge-estrogen Receptor Agonist. Ine-potrogen ephezulu ye-estrogenic lapho ihanjiswa ngomlomo, futhi ivame ukusetshenziswa njengengxenye ye-estrogenic ezindleleni zokuvimbela inzalo ngomlomo. I-Ethinyl estradiol ibopha kune-estrogen receptor tata futhi ingena kwi-nucleus, isebenze okubhalwe ku-DNA kwezakhi zofuzo ezibandakanya izimpendulo zamaselula e-estrogenic. Le ejenti iphinda ivimbele i-5-alpha reductase kwezicubu ezihlasele isifo, esehlisa amazinga e-testosterone futhi ingabambezela ukuqhubekela phambili komdlavuza wesinye. Ngaphezu kwemiphumela yayo ye-antineoplastic, i-ethinyl estradiol ivikela ngokumelene namathambo. Kumamodeli wezilwane, ukwelashwa kwesikhashana esifana nalesi sikhungo kukhonjisiwe ukuthi kuvikeleke isikhathi eside ekulweni nomdlavuza webele, kulingisa imiphumela ye-antitumor yokukhulelwa.

Izikhombo:

  • I-1: I-Archer DF, uThomas MA, uConard J, uMerkatz RB, uCreasy GW, uRoberts K, uPlagianos M, uBlithe D, uSitruk-Ware R. Umthelela kumaphrotheni anobuthi be-hepatic estrogen owisa unyaka owodwa wokukhipha i-Nestorone® no ethinyl estradiol. Ukuvimbela inzalo. 1 Jan; 2016 (93): 1-58. doi: 64 / j.contraception.10.1016. Epub 2015.09.008 Sep 2015. I-PubMed PMID: 25.
  • 2: Lobo Abascal P, Luzar-Stiffler V, Giljanovic S, Howard B, Weiss H, Trussell J. umehluko ekubikeni i-Pearl Indices e-United States nase-Europe: Gxila ezinsukwini ezingama-91 ezinwetshiwe ezihlanganisiwe zokuhlangana kokubeletha ngomlomo nabangaphansi- umthamo we-ethinyl estradiol supplementation. I-Eur J Contracept Reprod Ukunakekelwa Kwezempilo. 2016 Feb; 21 (1): 88-91. doi: 10.3109 / 13625187.2015.1059416. Epub 2015 Jun 26. I-PubMed PMID: 26115381.
  • I-3: I-Waellnitz K, i-Duijkers I, iKlipping C, i-Rautenberg T, i-Rohde B, ne-Zurth C. Isikhungo esiyisikhungo ezimbili, esinendawo evulekile, ucwaningo oluhleliwe lwe-ovulation inhibition olunama patches amathathu we-transdermal contracepts, ngalinye liqukethe amanani ahlukene e-ethinyl estradiol ne-gestodene ku- enempilo, abesifazane abasha. J Obstet Gynaecol. 2016 Jan; 36 (1): 106-13. doi: 10.3109 / 01443615.2015.1041882. Epub 2015 Sep 30. PubMed PMID: 26421957.
  • I-4: Patel G, King A, Dutta S, Korb S, Wade JR, Foulds P, Sumeray M. Ukuhlolwa kwemiphumela ethambile ye-CYP3A inhibitors atorvastatin kanye ne-ethinyl estradiol / norchedimate pa lomitapide pharmacokinetics ngezifundo ezinempilo. J Clin Pharmacol. 2016 Jan; 56 (1): 47-55. doi: 10.1002 / jcph.581. Epub 2015 Sep 10. I-PubMed PMID: 26120010.

UKUHLELWA KANYE Nesitatimende:

Le Material ithengiswa Ukusetshenziswa Kocwaningo Kuphela. Imibandela Yokuthengisa Faka isicelo. Hhayi Ukusetshenziswa Komuntu, noma Ezokwelapha, Izilwane, noma Ukusetshenziswa Kwasekhaya.


COA

I-HNMR

I-AAS eluhlaza inikeza ubumsulwa i-98% i-Raloxifene powder eluhlaza kubanikazi bomzimba noma ngamabhishi angaphansi komhlaba okusetshenziselwa ngomlomo.

I-AAS eluhlaza inikeza ubumsulwa i-98% i-Raloxifene powder eluhlaza kubanikazi bomzimba noma ngamabhishi angaphansi komhlaba okusetshenziselwa ngomlomo.

Ungadliwa

I-Raloxifene Raw Powder Recipes

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