I-Safest Muscle Booster Supplement: I-Urolithin A (UA) Powder AASraw
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Omunye wemigomo eyinhloko yabakhi bomzimba nabasubathi ukukhulisa imisipha ethambile futhi uthuthukise ithoni, kanye namandla, emisipha. Kungaba nzima ukufinyelela lo mphumela ngokuzivocavoca noma izinhlelo zokuqeqesha kuphela. Ukuhlela ukudla okuqinile, ukusetshenziswa kwama-macronutrients abalulekile, kanye nokusetshenziswa kwezithako ezithile zangaphambi kokujima kanye nangemuva kokujima kuyadingeka ukuze kube nokukhula kwemisipha okwanele ngesikhathi esinqunyiwe.

Kunezindlela eziningi zokuthuthukisa ukukhula kwemisipha yakho futhi ubone izinguquko ezibalulekile emzimbeni wakho, okubaluleke kakhulu okuwukudla amaprotheni anele. Ukudla amaprotheni ngakho konke ukudla kungazuzisa ukukhula kwemisipha yakho, njengoba ama-amino acid avela kulawa maprotheni esiza ukulungisa ukulimala kwemisipha futhi agcwalise izitolo zamaprotheni emisipha, ngemva kokuzivocavoca okukhulu. Ama-carbohydrate kufanele agwenywe ngokujwayelekile, ngaphandle kwangemuva kokuzivocavoca lapho ukukhula kwemisipha kuwumgomo.

Enye indlela esheshayo yokuthuthukisa ukukhula kwemisipha ukusetshenziswa kwe-steroids. Bavame ukuthola idumela elibi njengoba ezinye izinhlobo ze-steroid zivinjelwe ukusetshenziswa yinoma yimuphi umakhi womzimba noma umsubathi yiziphathimandla ezihambisanayo. Kodwa-ke, kunezinye izinhlobo eziningi eziphephile nezisemthethweni ukuthi zisetshenziswe, eziye zafakazelwa ukuthi zizuzisa ngezingcezu eziningi zezifundo zesayensi.

Ama-steroid angasetshenziswa ngokwezihloko, noma athathwe ngendlela yephilisi noma umjovo, ngqo emsipha. Inhloso yalezi steroids awukona nje ukwandisa ubukhulu bemisipha, okwenza kube nokukhula okuphawulekayo kwemisipha kodwa nokwandisa amandla emisipha. Abakhi bomzimba abasebenzisa i-steroids babika ukuthuthuka kokukhuthazela nokukhuthazela ejimini, okuyinto nakanjani inhlanganisela evumelana ne-steroids.

I-Urolithin A (UA) Impushana - 01

Uma kuqhathaniswa Ne-Steroid, Yiziphi Izinzuzo Ze-Urolithin A (UA)?

Uma inhlamba ezungeze ama-steroids ivaliwe kuwe futhi ufuna enye indlela, khona-ke Isengezo se-Urolithin A kungase kudingeke ukubhekisisa. I-Urolithin A powder iyi-booster yemisipha enamandla futhi ephephile, izinzuzo zayo eziye zasekelwa ubufakazi obuphathekayo besayensi. Izinzuzo zalesi sici se-muscle ziphindaphindiwe futhi zahlolwa ezifundweni eziningi ezahlukene, futhi ngayinye isekele izinzuzo ezicatshangelwayo. 

Ama-anabolic steroids abagijimi abawasebenzisayo angathuthukisa ukukhula kwemisipha ngokuphawulekayo kodwa imiphumela emibi yale mithi, njengokuncipha kosayizi wamasende ngenxa ye-testicular atrophy kanye nokungazali, idlula kude izinzuzo zomuthi. Yingakho kubalulekile ukubheka ezinye izindlela, futhi i-Urolithin A inamandla afanayo noma akhuphukayo, uma kuqhathaniswa, lapho ithuthukisa ubukhulu bemisipha. Kodwa-ke, imiphumela emibi ye-Urolithin A ayisondeli nokuba bucayi njengemiphumela emibi ye-steroids.

I-Urolithin A iyisengezo esiphephile uma kuqhathaniswa nesisebenza kahle esinezinzuzo zokulwa nokuguga, i-metabolic, neuroprotective, kanye ne-anti-obesity. Ngokusho kocwaningo olwenziwe ukuhlola izinzuzo zesithasiselo, kuphephile ukusetshenziswa komuntu. Ngaphezu kwalokho, abukho ubuthi obubikiwe noma imiphumela emibi ebikiwe, kuze kube manje. Ukusebenzisa umkhiqizo ofanele ngethamo elilungile kungasiza ukwehlisa ubungozi banoma yimiphi imiphumela emibi engaba khona kakhulu.

I-Urolithin A, selokhu yatholwa ngeminyaka yawo-2000s, isifundwe kabanzi ngezinzuzo zayo ezifana nokuqinisa imisipha kanye namakhono okuthuthukisa ukukhuthazela. Kodwa-ke, kunezinye izinzuzo ezimbalwa zenhlanganisela ezatholwa ngenxa yalezi zingcezu zocwaningo, futhi zibalulwe ngezansi:

  • Ukulawulwa kwezinkinga ze-metabolic

Lapho kuhlolwa ikhono le-Urolithin A supplement ukuze kuthuthukiswe ukukhuthazela kubantu asebekhulile, abacwaningi bathola ukuthi i-metabolite yanciphisa kakhulu inani le-ceramides ne-acylcarnitine emzimbeni. Lokhu kuvame ukubandakanyeka ezinkingeni ze-metabolic eziqondise i-mitochondria. Kungakho kwaphethwa ngokuthi i-Urolithin A ingasiza ekulawuleni ukuphazamiseka kwe-mitochondrial metabolic. 

  • Imiphumela engasebenzi kahle

Nakuba le nzuzo ye-Urolithin A supplement ingathakazelisi njengekhono layo lokuthuthukisa ukukhula kwemisipha, ibaluleke ngokufanayo. Ngokusho kocwaningo olwenziwe kumamodeli ezilwane, kwatholakala ukuthi ukusetshenziswa kwe-metabolite kuthuthukisa izimpawu ze-Alzheimer's, nakuba ucwaningo olwengeziwe luyadingeka ngaphambi kokuba lusetshenziswe njengendlela yokwelapha evamile.

  • Imiphumela yokulwa nokukhuluphala ngokweqile

I-Urolithin A yacwaningwa ngokuqhubekayo ngezinzuzo zayo ze-metabolic lapho enye yezinzuzo itholwa ngengozi phakathi nocwaningo olwalwenziwa ukuze kuhlaziywe ukusetshenziswa kwezithako ze-Urolithin A ekuthuthukiseni ukukhuthazela kwemisipha phakathi kwasebekhulile. 

Izinhlobo zezilwane ekudleni okunamafutha amaningi noma i-HFD zacwaningwa njengoba zinikezwe isithasiselo se-Urolithin A. I-Urolithin A kulawa magundane akhuluphele abangela ukuba mnyama kwezicubu ze-adipose ezimhlophe kwase kuthi, i-Urolithin A yathuthukisa i-thermogenesis yezicubu ze-adipose ensundu, ukuze kuncibilike amafutha. I-Urolithin A ayigcini nje ngokuncibilikisa amafutha kodwa futhi yatholakala ukuze ivimbele ukuzuza kwesisindo phakathi kwamagundane ayephakelwa i-HFD. Lo mphumela we-metabolic kanye ne-anti-obesity we-Urolithin A powder ungavula umhlaba omusha wamathuba kanye nokusetshenziswa kwe-metabolite.

Iyini i-Urolithin A (UA)?

I-Urolithin A iyinhlanganisela ye-organic ekhiqizwa i-ellagitannins yi-microbiota emathunjini. I-Urolithins iyinhlanganisela ye-polycyclic enamakha engama-metabolites akhiwe kusuka kuma-precursors afana ne-ellagic acid ne-ellagitannins, atholakala ezithelweni zemvelo ezifana nehalananda.

Ikhasi lepomegranate licebile I-Urolithin B kuyilapho i-Urolithin A ingenawo umthombo othile wokudla. Esikhundleni salokho, kwakhiwa ukuguqulwa kwama-tannins atholakala ezithelweni yi-gut flora. Ukwakheka kwemithombo yokudla ye-ellagitannins kushiwo etafuleni elingezansi. Le mithombo yokudla isebenza njengemithombo engaqondile ye-Urolithin A, phambi kwe-gut microbiota enempilo ekwazi ukwenza inqubo yokuguqula.

Umthombo wokudla I-Acid e-Ellagic
Izithelo 
Amajikijolo 150
Amajikijolo amnyama 90
Ama-Boysenberries 70
Ama-Cloudberry 315.1
emhlophe 269.9
Ama-raspberries 270
URose okhalweni 109.6
Ama-Strawberries 77.6
Ijamu le-Strawberry 24.5
Amajikijolo aphuzi 1900
Amantongomane (mg / g)
pecans 33
Ama-Walnuts 59
Iziphuzo (mg / L)
Ujusi wamapomegranate 811.1
I-cognac 31-55
Iwayini elibomvu elineminyaka engama-oak 33
I-Whisky 1.2
Imbewu (mg / g)
Amajikijolo amnyama 6.7
Amajikijolo abomvu 8.7
Ama-Boysenberries 30
i-Mango 1.2

I-Urolithin-A Isebenza Kanjani Ekuqiniseni Imisipha?

I-Urolithin A ithathe indawo ye-steroids 'emakethe njengoba iphephile futhi inamandla emisipha booster. Abahlinzeki be-Urolithin A bakhuthaza ukusetshenziswa kwalesi sengezo ngenxa yezinzuzo eziningi zomkhiqizo, okubaluleke kakhulu ukukhula kwemisipha. Amandla emisipha, ukukhula, nokukhuthazela kuncike kakhulu ekusebenzeni kwe-mitochondrial kumaseli. I-Mitochondria iwumthombo wamandla weseli, futhi inesibopho sokukhiqizwa kwe-ATP, okuyimali yamandla omzimba. 

-Kuthuthukiswe Amandla Emisipha Kwabadala

Njengoba umuntu ekhula, amandla emisipha, ubukhulu, nokukhuthazela kuncipha kakhulu. Lokho kungasolwa ngokuncipha kokusebenza kwe-mitochondria kanye nokuqoqwa okuphelele kwe-mitochondria ehlulekayo. Lokhu kuncipha kwe-mitophagy kudlala indima ebalulekile ekuvimbeleni asebekhulile ekwenzeni imisebenzi nemisebenzi yansuku zonke yokuphila. Isixazululo sale nkinga sitholakale siyi-Urolithin A powder. 

Kwakukhona olunye ucwaningo olwenziwa ngenhloso yokunquma umphumela we-Urolithin A emandleni emisipha nokukhuthazela kubantu asebekhulile, abathola ukwehla komsebenzi we-mitochondrial ngokukhula. 

Ngokusho kwabacwaningi abenza ucwaningo lomtholampilo, kube nesixazululo sokuhluleka kwe-mitophagy phakathi kwabahlanganyeli ocwaningweni, okubonisa ukucaciswa kwe-mitochondria engasebenzi kanye nokwenza ngcono impilo ye-mitochondrial iyonke. Uma kuqhathaniswa neqembu elithole i-placebo, ababambiqhaza banikeze i-placebo Isengezo se-Urolithin A kubika ukuthuthukiswa okuphawulekayo kokukhuthazela namandla emisipha emilenzeni nasezingalweni. Kube nokukhathala okuncishisiwe kanye nokuthuthukiswa okuphelele emandleni okwenza imisebenzi yansuku zonke. 

Abacwaningi baphinde baphawula ukuthi isengezo se-Urolithin A kungaba enye indlela yokuthuthukisa amandla emisipha namandla phakathi kwabantu asebekhulile abangakwazi ukuvivinya umzimba ngenxa yezinkinga zempilo yomzimba noma yengqondo. Ngokusho kweCenter for Disease Control and Prevention noma i-CDC, ukuvivinya umzimba nsuku zonke kungasiza ukulwa nezinkinga zokuhamba, izingozi zokuwa, nokunye ukuphazamiseka kokunyakaza kwasebekhulile. Kodwa-ke, uma lokhu kungenzeki, ukuthatha izithasiselo ze-Urolithin A kungaletha i-mitophagy emazingeni ajwayelekile, ngakho-ke, kube nomthelela ofanayo nowokuzivocavoca. 

-Ukuphathwa kwe-Duchenne Muscular Dystrophy

Kodwa-ke, ngezifo zemisipha eziwohlokayo njenge-Duchenne Muscular Dystrophy noma i-DMD, okuqukethwe kwe-mitochondrial kumaseli akulungile futhi i-mitochondria ekhona ayisebenzi kahle. Ngaphezu kwalokho, ku-DMD, i-mitophagy inciphe kakhulu, okuyinqubo lapho imizimba yethu ikhipha i-mitochondria engasebenzi futhi iphinde isebenzise okuqukethwe ukuze kuhlangatshezwane nezidingo zamandla aphezulu omzimba. 

Olunye locwaningo olwenziwe ukufunda imiphumela ye I-Urolithin Impushana ekukhuleni kwemisipha egxile emthelela owake waba nawo ku-mitophagy. Abacwaningi bathola ukuthi ukwesekwa nge-Urolithin A kwathuthukisa kakhulu amazinga e-mitophagy, kuwabuyisela esimweni esivamile ezigulini ze-muscular dystrophy. Le miphumela ibonwe kuzo zombili izinhlobo zezilwane nezihloko zabantu, okubonisa ukuthi i-Urolithin A ingasetshenziswa ngempumelelo ukuphatha izimpawu ze-muscular dystrophies. Ngaphezu kwalokho, abacwaningi baqophe ukwenyuka okungamaphesenti angama-40 kumazinga okusinda amamodeli ezilwane anikezwe isithasiselo se-Urolithin A uma kuqhathaniswa nalabo abangazange bakuthole okungeziwe. Amandla okubamba namandla okugijima anyuke ngamaphesenti angu-31 namaphesenti angu-45, ngokulandelana, kulezi zinhlobo zezilwane. 

Enye inzuzo ebalulekile ye-Urolithin A supplementation eyaqashelwa phakathi nalolu cwaningo ukuthi yehlisa i-fibrosis noma izibazi zenhliziyo kanye ne-diaphragm yamagundane ane-DMD. Lena inkinga ebalulekile ye-DMD manje engalawulwa ngayo I-Urolithin Impushana.

I-Urolithin A (UA) Impushana -03

Ungayithenga Kuphi I-Urolithin A Engcono Kakhulu (UA) powder Online?

Kukhona abahlinzeki be-Urolithin A abambalwa ku-inthanethi abanamawebhusayithi abo azinikele abangakhethwa ukuze bathenge imetabolite. Abathengisi bezitolo ezinkulu bavumela abasebenzisi ukuthi bathenge i-Urolithin A powder ku-inthanethi, ngokudiliva okulula nokufika ngesikhathi. Laba bathengisi baphatha kuphela impushana, hhayi izithasiselo ezenziwe ngale metabolite. Izithako ze-Urolithin A zingathengwa ngokuqondile kumkhiqizo owukhethile noma kwa-Amazon.

Ngaphambi kokuthenga i-wholesale noma izithasiselo, kunconywa kakhulu ukuthi uhlole ukubuyekezwa kwemikhiqizo ukuze uqinisekise ukuthi umkhiqizo wangempela, onamandla, futhi osebenzayo uyathengwa. Kukhona ama-dupe amaningi emakethe futhi ngezinye izikhathi, umkhiqizo othengwayo ungase ungcoliswe ezinye izithako noma ubuthi. Kungcono ukwenza ukuhlaziywa okuphelele kokuphepha nokuhlanzeka kwe-Urolithin A powder ngaphambi koku-oda ngisho nenani elincane kakhulu.

Isengezo se-Urolithin A sitholakala ngezindlela ezihlukene njengempuphu noma amaphilisi ejeli athambile. I-oda ngokuqondile ku-Urolithin. Umphakeli angenza kube lula kuwe ukuthi uzikhethele uhlobo olufanele lwesithasiselo. Uma ifomu selinqunyiwe, kubalulekile ukuthi uzikhethele umthamo ofanele. Kubalulekile ukukhumbula ukuthi i-Urolithin A powder kufanele ithathwe kanye kuphela ngosuku, umthamo ngamunye ube ngu-500mg. 

Kunemithombo yokudla eminingana ye-Urolithin A kodwa akwanele ukusebenzisa ukudla okucebile izandulela ze-Urolithin A. Kufanele kube nezinhlobo ezimbili zebhaktheriya ezithile ku-gut flora ukuze i-ellagitannins igaywe ku-Urolithin A. Lezi ezimbili izinhlobo, I-Gordonibacter pamelaeae (DSM 19378T) kanye ne-Gordonibacter urolithinfaciens (DSM 27213T).

Uma lezi zinhlobo zingekho ku-flora yamathumbu, khona-ke umuntu othintekile ngeke abe nokukhiqizwa kwe-Urolithin A emzimbeni. Abantu abanjalo kufanele bathathe izithasiselo ukuze bavale ukuntuleka kokuguqulwa kwe-Urolithin emzimbeni.

Yimiphi Imiphumela Esingayibona Ngemva Kwe-Urolithin-A Powder?

I-Urolithin I-A ifakazelwe, ngocwaningo lwesayensi nezifundo, ukuthi inomphumela wokulwa nokuguga emandleni emisipha, usayizi, nokukhuthazela. Zonke izinzuzo zisekelwa ubufakazi besayensi futhi isikhathi esincane lapho lezi zifundo zenziwa izinyanga ezine. Ucwaningo lwathatha izinyanga ezine noma ngaphezulu, futhi abacwaningi abaningi bathi izithasiselo ze-Urolithin A zidinga okungenani izinyanga ezine ukukhiqiza izinzuzo ze-mitophagy kanye ne-metabolic.

Izikhombo:

[1]Guada M, Ganugula R, Vadhanam M, Ravi Kumar MNV. I-Urolithin A Yehlisa I-Nephrotoxicity Ebangelwa I-Cisplatin Ngokuvimbela Ukuvuvuka Kwezinso kanye ne-Apoptosis Kumodeli Yegundane Lokuhlola. J Pharmacol Exp Ther. 2017;363(1):58-65. doi:10.1124/jpet.117.242420.
[2] “Isaziso se-FDA GRAS GRN No. 791: urolithin A”. I-US Food and Drug Administration. 20 Disemba 2018. Ibuyiselwe ngomhla ka-25 Agasti 2020.
[3]Landete JM (2011). "I-Ellagitannins, i-ellagic acid kanye nama-metabolites atholakalayo: Ukubuyekezwa mayelana nomthombo, umzimba, imisebenzi kanye nempilo". Food Research International. 44 (5): 1150–1160. doi:10.1016/j.foodres.2011.04.027.
[4] Johanningsmeier SD, Harris GK (2011-02-28). "Ipomegranate njengokudla okusebenzayo kanye nomthombo we-nutraceutical". Ukubuyekezwa Konyaka Kwesayensi Yokudla Nobuchwepheshe. 2 (1): 181–201. doi:10.1146/annurev-food-030810-153709. PMID 22129380.
[5]I-Han QA, i-Yan C, i-Wang L, i-Li G, i-Xu Y, i-Xia X. I-Urolithin A inciphisa ukungasebenzi kahle kwe-endothelial okubangelwa i-ox-LDL ngokwengxenye ngokumodela indlela ye-microRNA-27 kanye ne-ERK/PPAR-γ. I-Mol Nutr Food Res. 2016;60(9):1933-1943. doi:10.1002/mnfr.201500827.

I-AASraw ingumkhiqizi ochwepheshe we-Urolithin A (UA) powder onelebhu ezimele kanye nefektri enkulu njengokusekela, konke ukukhiqizwa kuzokwenziwa ngaphansi komthetho we-CGMP kanye nesistimu yokulawula ikhwalithi elandelekayo. Uhlelo lokuhlinzeka luzinzile, kokubili ama-oda okuthengisa kanye nama-wholesale amukelekile.Siyakwamukela ukuze ufunde ulwazi olwengeziwe mayelana ne-AASraw!

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